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The Foundation operates two medical centres that provide care for the elderly, sickle cell disorder and maternal and child care. The Sickle Cell Care department of the Centre apart from disease management and care also offers counselling and outreach services. It is the most functional in a region that has a combined population of about 16 ...
Cell lineage. Cell lineage denotes the developmental history of a tissue or organ from the fertilized embryo. [1] This is based on the tracking of an organism's cellular ancestry due to the cell divisions and relocation as time progresses, this starts with the originator cells and finishing with a mature cell that can no longer divide.
The human disease sickle cell anemia is caused by a genetic mutation in the codon for the sixth amino acid of the blood protein beta-hemoglobin.The normal DNA sequence G-A-G codes for the amino acid glutamate, while the mutation changes the middle adenine to a thymine, leading to the sequence G-T-G (G-U-G in the mRNA).
Southeast Asian ovalocytosis. It is hereditary hemolytic anaemia in which the red blood cell is oval-shaped. The primary defect in SAO differs significantly from other forms of elliptocytosis in that it is a defect in the gene coding for a protein that is not directly involved in the cytoskeleton scaffolding of the cell.
Poikilocytosis is variation in the shapes of red blood cells. Poikilocytes may be oval, teardrop-shaped, sickle-shaped or irregularly contracted. Normal red blood cells are round, flattened disks that are thinner in the middle than at the edges. A poikilocyte is an abnormally-shaped red blood cell. [1] Generally, poikilocytosis can refer to an ...
Bans on communist symbols. Symbols that are most commonly associated with communism: the hammer and sickle, the red star, and the red banner. Countries where: All communist symbols are banned. Certain communist symbols are banned. Communist symbols were formerly banned. Communist symbols have been banned, in part or in whole, by a number of the ...
A vaso-occlusive crisis is a common painful complication of sickle cell anemia in adolescents and adults. It is a form of sickle cell crisis. Sickle cell anemia – most common in those of African, Hispanic, and Mediterranean origin – leads to sickle cell crisis when the circulation of blood vessels is obstructed by sickled red blood cells, causing ischemic injuries. The most common ...
Molar mass. 146 232.04 g·mol −1. Crizanlizumab, sold under the brand name Adakveo among others, is a monoclonal antibody medication that binds to P-selectin. [3] It is a medication used to reduce the frequency of vaso-occlusive crisis in people aged 16 years and older who have sickle cell anemia. [3] [4] [6] It is given by injection into a vein.
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