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Sickle cell disease is a group of inherited blood disorders that affect the shape and function of red blood cells. It can cause pain, anemia, infections, stroke, and organ damage. Learn about the genetics, diagnosis, and management of sickle cell disease.
Sickle cell trait is a condition where a person has one abnormal allele of the hemoglobin beta gene (genotype AS) and produces both normal and abnormal hemoglobin. It is associated with some resistance to malaria, but also rare complications such as sickle cell crisis, renal medullary carcinoma, and urinary tract infection.
The US Food and Drug Administration on Friday approved two gene-based treatments for sickle cell disease, including the first therapy that uses the gene-editing technique CRISPR, opening a new era ...
Learn how inherited changes in DNA increase resistance to malaria and result in blood disorders. Find out how malaria exerts evolutionary pressure on human genome and how it affects red blood cells.
The FDA on Friday also approved a second treatment for sickle cell disease, called Lyfgenia, a gene therapy from drugmaker Bluebird Bio. Both treatments work by genetically modifying a patient’s ...
By Leroy Leo and Bhanvi Satija (Reuters) -The U.S. Food and Drug Administration (FDA) on Friday approved two gene therapies for sickle cell disease, making one of them the first treatment in the ...
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