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  2. Sickle cell disease - Wikipedia

    en.wikipedia.org/wiki/Sickle_cell_disease

    Migration of substantial populations from these high-prevalence areas to low-prevalence countries in Europe has dramatically increased in recent decades and in some European countries, sickle cell disease has now overtaken more familiar genetic conditions such as haemophilia and cystic fibrosis. In 2015, it resulted in about 114,800 deaths.

  3. Sickle cell trait - Wikipedia

    en.wikipedia.org/wiki/Sickle_cell_trait

    Hematology. Sickle cell trait describes a condition in which a person has one abnormal allele of the hemoglobin beta gene (is heterozygous ), but does not display the severe symptoms of sickle cell disease that occur in a person who has two copies of that allele (is homozygous ). Those who are heterozygous for the sickle cell allele produce ...

  4. Genetic studies on Arabs - Wikipedia

    en.wikipedia.org/wiki/Genetic_studies_on_Arabs

    Genetic studies on Arabs. Genetic studies on Arabs refers to the analyses of the genetics of ethnic Arab people in the Middle East and North Africa and parts of Sub-Sahara Africa where Black Arabs claim descent. Arabs are genetically diverse as a result of their intermarriage and mixing with indigenous people of the pre-Islamic Middle East and ...

  5. The world's first gene therapy for sickle cell disease has ...

    www.aol.com/news/uk-becomes-1st-country-approve...

    Britain's medicines regulator has authorized the world's first gene therapy treatment for sickle cell disease, in a move that could offer relief to thousands of people with the crippling disease ...

  6. Promising new gene therapies for sickle cell are out of ... - AOL

    www.aol.com/news/promising-gene-therapies-sickle...

    The price tags for the two sickle cell therapies in the U.S. are $3.1 million and $2.2 million although the cost for gene therapies can vary by country. The process of giving the therapies is just ...

  7. Human genetic resistance to malaria - Wikipedia

    en.wikipedia.org/wiki/Human_genetic_resistance...

    Sickle cell – The gene for HbS associated with sickle-cell is today distributed widely throughout sub-Saharan Africa, the Middle East, and parts of the Indian subcontinent, where carrier frequencies range from 5–40% or more of the population.

  8. FDA approves gene therapy for sickle cell disease: 'One ... - AOL

    www.aol.com/fda-approves-gene-therapy-sickle...

    Now, 33, Stephenson was one of the first to receive sickle cell gene therapy in a clinical trial six years ago. Before the treatment, Stephenson lived her life on a razor's edge.

  9. Sub-Saharan Africa - Wikipedia

    en.wikipedia.org/wiki/Sub-Saharan_Africa

    Regional Map portraying the four regions of Sub-Saharan Africa with North Africa in gray. Only six African countries are not geopolitically a part of sub-Saharan Africa: Algeria, Egypt, Libya, Morocco, Tunisia and Western Sahara (claimed by Morocco); they form the UN subregion of Northern Africa, which also makes up the largest bloc of the Arab ...