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Sickle cell disease is a group of blood disorders inherited from both parents, causing abnormal red blood cells that can lead to pain, anemia, infections, and organ damage. Learn about the symptoms, diagnosis, treatment, and prevention of sickle cell disease and its subtypes.
Sickle cell trait is a condition where a person has one abnormal allele of the hemoglobin beta gene (genotype AS) and produces both normal and abnormal hemoglobin. It is associated with some resistance to malaria, but also rare complications such as sickle cell crisis, renal medullary carcinoma, and urinary tract infection.
SCDAA is a nonprofit organization that supports research, education and funding for sickle cell disease and related conditions. It has over 40 branches across the US and hosts events such as the National Sickle Cell Walk and the Sickle Cell Disease National Convention.
The price tags for the two sickle cell therapies in the U.S. are $3.1 million and $2.2 million although the cost for gene therapies can vary by country. The process of giving the therapies is just ...
Learn about the origin, evolution, and treatment of malaria, a deadly disease that has affected humans for millions of years. The article covers the prehistoric period, the ancient and medieval periods, the modern period, and the global eradication efforts.
The price tags for the two sickle cell therapies in the U.S. are $3.1 million and $2.2 million although costs can vary by country. The process of giving the therapies is just as big a hurdle.
Beta thalassemia is a group of inherited blood disorders caused by mutations in the HBB gene that affect hemoglobin production. Beta thalassemia major is the most severe form that requires lifelong transfusions and can lead to organ failure and death.
A South African geneticist and medical scientist who discovered the genetic resistance to malaria and developed CellCept. He worked at Oxford, London, Nairobi, and California, and published over 400 papers and 12 books.