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  2. Sickle cell disease - Wikipedia

    en.wikipedia.org/wiki/Sickle_cell_disease

    Sickle cell disease ( SCD ), also simply called sickle cell, is a group of hemoglobin-related blood disorders typically inherited. [2] The most common type is known as sickle cell anemia. [2] It results in an abnormality in the oxygen-carrying protein haemoglobin found in red blood cells. [2] This leads to a rigid, sickle -like shape under ...

  3. Sickle cell trait - Wikipedia

    en.wikipedia.org/wiki/Sickle_cell_trait

    Hematology. Sickle cell trait describes a condition in which a person has one abnormal allele of the hemoglobin beta gene (is heterozygous ), but does not display the severe symptoms of sickle cell disease that occur in a person who has two copies of that allele (is homozygous ). Those who are heterozygous for the sickle cell allele produce ...

  4. Felix Konotey-Ahulu - Wikipedia

    en.wikipedia.org/wiki/Felix_Konotey-Ahulu

    Felix Israel Domeno Konotey-Ahulu FGA, FRCPSG, FRCP, FWACP (born 12 July 1930) is a Ghanaian physician and scientist who is Kwegyir Aggrey Distinguished Professor of Human Genetics at the University of Cape Coast, Ghana, and a consultant physician/ genetic counsellor, Haemoglobinopathy/Sickle Cell States, in Harley Street, London. [4]

  5. Middle-earth - Wikipedia

    en.wikipedia.org/wiki/Middle-earth

    Middle-earth is the human-inhabited world, that is, the central continent of the Earth, in Tolkien's imagined mythological past. Tolkien's most widely read works, The Hobbit and The Lord of the Rings, are set entirely in Middle-earth. "Middle-earth" has also become a short-hand term for Tolkien's legendarium, his large body of fantasy writings ...

  6. The world's first gene therapy for sickle cell disease has ...

    www.aol.com/news/uk-becomes-1st-country-approve...

    Britain's medicines regulator has authorized the world's first gene therapy treatment for sickle cell disease, in a move that could offer relief to thousands of people with the crippling disease ...

  7. Sickle Cell Disease Association of America - Wikipedia

    en.wikipedia.org/wiki/Sickle_Cell_Disease...

    The Sickle Cell Disease Association of America, Inc. originated in Racine, Wisconsin. Representatives from 15 different community-based sickle cell organizations came together at Wingspread, a community center, as guest of the Johnson Foundation. There was a common belief that there was a need for national attention to sickle cell disease.

  8. Thalassemia - Wikipedia

    en.wikipedia.org/wiki/Thalassemia

    16,800 (2015) [6] Thalassemias are inherited blood disorders that result in abnormal hemoglobin. [7] Symptoms depend on the type of thalassemia and can vary from none to severe. [1] Often there is mild to severe anemia (low red blood cells or hemoglobin) as thalassemia can affect the production of red blood cells and also affect how long the ...

  9. Sub-Saharan Africa - Wikipedia

    en.wikipedia.org/wiki/Sub-Saharan_Africa

    The region produces 49% of the world's diamonds . Sub-Saharan Africa has been the focus of an intense race for oil by the West, China, India, and other emerging economies, even though it holds only 10% of proven oil reserves, less than the Middle East. This race has been referred to as the second Scramble for Africa.

  10. Anthony Clifford Allison - Wikipedia

    en.wikipedia.org/wiki/Anthony_Clifford_Allison

    Anthony Clifford Allison (21 August 1925 – 20 February 2014) was a South African geneticist and medical scientist who made pioneering studies on the genetic resistance to malaria. [2] Clark completed his primary schooling in Kenya, completed his higher education in South Africa, and obtained a BSc in medical science from the University of the ...

  11. Sickle cell-beta thalassemia - Wikipedia

    en.wikipedia.org/wiki/Sickle_cell-beta_thalassemia

    Sickle cell-beta thalassemia is caused by inheritance of a sickle cell allele from one parent and a beta thalassemia allele from the other. Mutations. A sickle allele is always the same mutation of the beta-globin gene (glutamic acid to valine at amino acid six). In contrast, beta-thalassemia alleles can be created by many different mutations ...