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Sickle cell disease (SCD), also simply called sickle cell, is a group of hemoglobin-related blood disorders typically inherited. The most common type is known as sickle cell anemia. It results in an abnormality in the oxygen-carrying protein haemoglobin found in red blood cells.
The Food and Drug Administration on Friday approved a powerful treatment for sickle cell disease, a devastating illness that affects more than 100,000 Americans, the majority of whom are Black.
He found that the prevalence of sickle-cell trait (heterozygous condition) among people inhabiting coastal areas was higher than 20%. (At the time the highest record was 8% among African-Americans.)
Lemuel Whitley Diggs (January 8, 1900 – January 8, 1995) was an American pathologist who specialized in sickle cell anemia and hematology. Biography. Diggs was born in Hampton, Virginia, but spent most of his life and did most of his work in Memphis, Tennessee.
Research. While at Caltech, Itano joined the lab of Linus Pauling and began working on sickle cell anemia, a genetic disease that Pauling was interested in. Pauling was convinced that sickle cell disease was caused by defective hemoglobin, and set Itano to find out what made sickle cell hemoglobin chemically different.
Sickle Cell Anemia, a Molecular Disease" is a 1949 scientific paper by Linus Pauling, Harvey A. Itano, Seymour J. Singer and Ibert C. Wells that established sickle-cell anemia as a genetic disease in which affected individuals have a different form of the metalloprotein hemoglobin in their blood.
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