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  2. Malaria - Wikipedia

    en.wikipedia.org/wiki/Malaria

    Sickle cell trait causes a change in the haemoglobin molecule in the blood. Normally, red blood cells have a very flexible, biconcave shape that allows them to move through narrow capillaries ; however, when the modified haemoglobin S molecules are exposed to low amounts of oxygen, or crowd together due to dehydration, they can stick together ...

  3. Osteoporosis - Wikipedia

    en.wikipedia.org/wiki/Osteoporosis

    Frequency. 15% (50 year olds), 70% (over 80 year olds) [7] Osteoporosis is a systemic skeletal disorder characterized by low bone mass, micro-architectural deterioration of bone tissue leading to more porous bone, and consequent increase in fracture risk. It is the most common reason for a broken bone among the elderly. [3]

  4. Hemoglobin E - Wikipedia

    en.wikipedia.org/wiki/Hemoglobin_E

    Hemoglobin E ( HbE) is an abnormal hemoglobin with a single point mutation in the β chain. At position 26 there is a change in the amino acid, from glutamic acid to lysine (E26K). Hemoglobin E is very common among people of Southeast Asian, Northeast Indian, Sri Lankan and Bangladeshi descent. [1] [2]

  5. Hammer and sickle - Wikipedia

    en.wikipedia.org/wiki/Hammer_and_sickle

    The hammer and sickle symbol. The hammer and sickle symbol and red star. The hammer and sickle ( Unicode: U+262D ☭ HAMMER AND SICKLE) is a communist symbol representing proletarian solidarity between agricultural and industrial workers. It was first adopted during the Russian Revolution at the end of World War I, the hammer representing ...

  6. Iron-deficiency anemia - Wikipedia

    en.wikipedia.org/wiki/Iron-deficiency_anemia

    Iron-deficiency anemia is anemia caused by a lack of iron. [3] Anemia is defined as a decrease in the number of red blood cells or the amount of hemoglobin in the blood. [3] When onset is slow, symptoms are often vague such as feeling tired, weak, short of breath, or having decreased ability to exercise. [1]

  7. Isosthenuria - Wikipedia

    en.wikipedia.org/wiki/Isosthenuria

    Isosthenuria refers to the excretion of urine whose specific gravity (concentration) is neither greater (more concentrated) nor less (more diluted) than that of protein-free plasma, typically 1.008-1.012. [1] Isosthenuria reflects damage to the kidney's tubules or the renal medulla . A closely related term is hyposthenuria, where the urine has ...

  8. Balancing selection - Wikipedia

    en.wikipedia.org/wiki/Balancing_selection

    A well-studied case is that of sickle cell anemia in humans, a hereditary disease that damages red blood cells. Sickle cell anemia is caused by the inheritance of an allele (HgbS) of the hemoglobin gene from both parents. In such individuals, the hemoglobin in red blood cells is extremely sensitive to oxygen deprivation, which results in ...

  9. Overdominance - Wikipedia

    en.wikipedia.org/wiki/Overdominance

    Overdominance. Overdominance is a phenomenon in genetics where the phenotype of the heterozygote lies outside the phenotypical range of both homozygous parents. Overdominance can also be described as heterozygote advantage regulated by a single genomic locus, wherein heterozygous individuals have a higher fitness than homozygous individuals.