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  2. Sickle cell disease - Wikipedia

    en.wikipedia.org/wiki/Sickle_cell_disease

    Signs of sickle cell disease usually begin in early childhood. The severity of symptoms can vary from person to person, as can the frequency of crisis events. Sickle cell disease may lead to various acute and chronic complications, several of which have a high mortality rate. First events

  3. Sickle cell trait - Wikipedia

    en.wikipedia.org/wiki/Sickle_cell_trait

    Sickle cell trait describes a condition in which a person has one abnormal allele of the hemoglobin beta gene (is heterozygous), but does not display the severe symptoms of sickle cell disease that occur in a person who has two copies of that allele (is homozygous).

  4. Acute chest syndrome - Wikipedia

    en.wikipedia.org/wiki/Acute_chest_syndrome

    Signs and symptoms. The crisis is a common complication in sickle-cell patients and can be associated with one or more symptoms including fever, cough, excruciating pain, sputum production, shortness of breath, or low oxygen levels. [2]

  5. Vaso-occlusive crisis - Wikipedia

    en.wikipedia.org/wiki/Vaso-occlusive_crisis

    Symptoms: acute, severe pain: Diagnostic method: There is no test to confirm a vaso-occlusive crisis, but tests can be done to rule out other causes. Patients with vaso-occlusive crisis present with pain (mild to severe) and a history of sickle cell anemia. Differential diagnosis: Neuropathic pain, hyperalgesia, osteomyelitis

  6. Glucose-6-phosphate dehydrogenase deficiency - Wikipedia

    en.wikipedia.org/wiki/Glucose-6-phosphate_de...

    It is an inborn error of metabolism that predisposes to red blood cell breakdown. Most of the time, those who are affected have no symptoms. Following a specific trigger, symptoms such as yellowish skin, dark urine, shortness of breath, and feeling tired may develop. Complications can include anemia and newborn jaundice.

  7. Sideroblastic anemia - Wikipedia

    en.wikipedia.org/wiki/Sideroblastic_anemia

    Symptoms and signs. Symptoms of sideroblastic anemia include skin paleness, fatigue, dizziness, and enlarged spleen and liver. Heart disease, liver damage, and kidney failure can result from iron buildup in these organs. Symptoms of sideroblastic anemia usually resemble the common symptoms of anemia.

  8. Anemia - Wikipedia

    en.wikipedia.org/wiki/Anemia

    There may be signs of specific causes of anemia, e.g. koilonychia (in iron deficiency), jaundice (when anemia results from abnormal break down of red blood cells – in hemolytic anemia), nerve cell damage (vitamin B 12 deficiency), bone deformities (found in thalassemia major) or leg ulcers (seen in sickle-cell disease).

  9. Sickle cell retinopathy - Wikipedia

    en.wikipedia.org/wiki/Sickle_cell_retinopathy

    Eye examination. Treatment. Medical, laser and surgery. Sickle cell retinopathy can be defined as retinal changes due to blood vessel damage in the eye of a person with a background of sickle cell disease. It can likely progress to loss of vision in late stages due to vitreous hemorrhage or retinal detachment. [1]

  10. Aplastic anemia - Wikipedia

    en.wikipedia.org/wiki/Aplastic_anemia

    Aplastic anemia causes a deficiency of all blood cell types: red blood cells, white blood cells, and platelets. It occurs most frequently in people in their teens and twenties but is also common among the elderly. It can be caused by heredity, immune disease, or exposure to chemicals, drugs, or radiation. However, in about half of cases, the ...

  11. Hemoglobin Lepore syndrome - Wikipedia

    en.wikipedia.org/wiki/Hemoglobin_Lepore_syndrome

    Sickle cell-Hb Lepore Boston syndrome is a type of sickle cell disease (HbS) that differs from homozygous sickle cell disease where both parents carry sickle hemoglobin. In this variant one parent has the sickle cell hemoglobin the second parent has Hb Lepore Boston, the only one of the three variants described in association with HbS.

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