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  2. Population history of West Africa - Wikipedia

    en.wikipedia.org/wiki/Population_history_of_West...

    Amid the Green Sahara, the mutation for sickle cell originated in the Sahara [125] or in the northwest forest region of western Central Africa (e.g., Cameroon) [125] [135] by at least 7,300 years ago, [125] [135] though possibly as early as 22,000 years ago.