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  2. Hydroxycarbamide - Wikipedia

    en.wikipedia.org/wiki/Hydroxycarbamide

    Hydroxycarbamide, also known as hydroxyurea, is a medication used in sickle-cell disease, essential thrombocythemia, chronic myelogenous leukemia, polycythemia vera, and cervical cancer. [4] [5] In sickle-cell disease it increases fetal hemoglobin and decreases the number of attacks. [4] It is taken by mouth. [4]

  3. Sickle cell retinopathy - Wikipedia

    en.wikipedia.org/wiki/Sickle_cell_retinopathy

    Proliferative sickle retinopathy is the most severe ocular complication of sickle cell disease. Even though PSCR begins in the first decade of life, the condition remains asymptomatic and unnoticed until visual symptoms occur due to vitreous hemorrhage or retinal detachment.

  4. FDA advisers review sickle cell treatment that could cure the ...

    www.aol.com/fda-advisers-review-sickle-cell...

    Because of a gene mutation, sickle cell anemia causes those red blood cells to break down early — taking a sickle or c-shape that carries less oxygen. It can lead to blocked blood flow, pain ...

  5. Asplenia - Wikipedia

    en.wikipedia.org/wiki/Asplenia

    Acquired asplenia occurs for several reasons: . Following splenectomy due to splenic rupture from trauma or because of tumor; After splenectomy with the goal of interfering with splenic function, as a treatment for diseases (e.g. idiopathic thrombocytopenic purpura, thalassemia, spherocytosis), in which the spleen's usual activity exacerbates the disease

  6. Autosplenectomy - Wikipedia

    en.wikipedia.org/wiki/Autosplenectomy

    Autosplenectomy can occur in cases of sickle-cell disease where the misshapen cells block blood flow to the spleen, causing scarring and eventual atrophy of the organ. [2] Autosplenectomy is a rare condition that is linked to certain diseases but is not a common occurrence.

  7. Aplastic anemia - Wikipedia

    en.wikipedia.org/wiki/Aplastic_anemia

    However, in people with conditions where the cells die early (such as sickle cell disease), parvovirus infection can lead to severe anemia. [15] [16] More frequently, parvovirus B19 is associated with aplastic crisis, which involves only red blood cells (despite the name). Aplastic anemia involves all cell lines.

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