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  2. Down syndrome - Wikipedia

    en.wikipedia.org/wiki/Down_syndrome

    15–20 wks 81% 5% Measures the maternal serum alpha-fetoprotein, unconjugated estriol, hCG, and inhibin-A Integrated test 15–20 wks 94–96% 5% Is a combination of the quad screen, PAPP-A, and NT Cell-free fetal DNA: From 10 wks [119] 96–100% [116] 0.3% [120] A blood sample is taken from the mother by venipuncture and is sent for DNA analysis.

  3. Caspian Sea - Wikipedia

    en.wikipedia.org/wiki/Caspian_Sea

    The Caspian Sea is the world's largest inland body of water, often described as the world's largest lake and sometimes referred to as a full-fledged sea. [2] [3] [4] An endorheic basin, it lies between Europe and Asia: east of the Caucasus, west of the broad steppe of Central Asia, south of the fertile plains of Southern Russia in Eastern Europe, and north of the mountainous Iranian Plateau.