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In people with sickle-cell disease or other forms of chronic hemolytic anemia, a blood disorder, the infection can precipitate an aplastic crisis, wherein the bone marrow of the individual will suddenly stop producing red blood cells. [1] [2] A 2019 systematic review examined the rates of parvovirus B19 infection among daycare workers.
Both sickle-cell disease and thalassemia are more common in malaria areas, because these mutations convey some protection against the parasite. Polycythemias (or erythrocytoses) are diseases characterized by a surplus of red blood cells. The increased viscosity of the blood can cause a number of symptoms.
Taking the example of sickle-cell disease, in an emergency room, knowing the geographic origin of a patient may help a doctor doing an initial diagnosis if a patient presents with symptoms compatible with this disease. This is unreliable evidence with the disease being present in many different groups as noted above with the trait also present ...
Sampat Tukaram Ramteke (Aug 1949 - Nov 2017) was an engineer and social activist from Nagpur, Maharashtra, India.In 2018, he was conferred the Padma Shri civilian honour posthumously, for his contribution in raising awareness in India about the sickle cell disease.
It is possible for a person to have both the gene for hemoglobin S (the form associated with sickle cell anemia) and the gene for hemoglobin C; this state is called hemoglobin SC disease, and is generally more severe than hemoglobin C disease, but milder than sickle cell anemia.
Proliferative sickle retinopathy is the most severe ocular complication of sickle cell disease. Even though PSCR begins in the first decade of life, the condition remains asymptomatic and unnoticed until visual symptoms occur due to vitreous hemorrhage or retinal detachment.
People with hemoglobin D trait do not have Hemoglobin D disease or sickle cell disease. They cannot develop these diseases later in life. They cannot develop these diseases later in life. While Hemoglobin D can be detected without a DNA test, one is needed to ascertain that a person who carries Hemoglobin D carries hemoglobin D-Punjab.
Autosplenectomy can occur in cases of sickle-cell disease where the misshapen cells block blood flow to the spleen, causing scarring and eventual atrophy of the organ. [2] Autosplenectomy is a rare condition that is linked to certain diseases but is not a common occurrence. It is also seen in systemic lupus erythematosus (SLE).
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