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114,800 (2015) [8] Sickle cell disease (SCD), also simply called sickle cell, is a group of hemoglobin-related blood disorders typically inherited. [2] The most common type is known as sickle cell anemia. [2] It results in an abnormality in the oxygen-carrying protein haemoglobin found in red blood cells. [2]
Genetics is the study of genes, genetic variation, and heredity in organisms. [1][2][3] It is an important branch in biology because heredity is vital to organisms' evolution. Gregor Mendel, a Moravian Augustinian friar working in the 19th century in Brno, was the first to study genetics scientifically.
Hemoglobin S (α 2 β S 2) – A variant form of hemoglobin found in people with sickle cell disease. There is a variation in the β-chain gene, causing a change in the properties of hemoglobin, which results in sickling of red blood cells. Hemoglobin C (α 2 β C 2) – Another variant due to a variation
1 in 10,000 people [2] Spinal muscular atrophy (SMA) is a rare neuromuscular disorder that results in the loss of motor neurons and progressive muscle wasting. [3][4][5] It is usually diagnosed in infancy or early childhood and if left untreated it is the most common genetic cause of infant death. [6] It may also appear later in life and then ...
The Human Genome Project was organized to map and to sequence the human genome. A fundamental step in the project was the release of a detailed genomic map by Jean Weissenbach and his team at the Genoscope in Paris. [21] [22] Reference genome sequences and maps continue to be updated, removing errors and clarifying regions of high allelic ...
Upon fusing with the cancer cell, the macrophages (smaller white cells) inject toxins that kill the tumor cell. Immunotherapy for the treatment of cancer is an active area of medical research. [141] The main response of the immune system to tumors is to destroy the abnormal cells using killer T cells, sometimes with the assistance of helper T ...
A trifecta of bearish factors could send stocks lower by about 10% within the next few weeks, according to Renaissance Macro Research founder and technical strategist Jeff DeGraaf. In an interview ...
Mitochondrial DNA is the small circular chromosome found inside mitochondria. These organelles, found in all eukaryotic cells, are the powerhouse of the cell. [ 1 ] The mitochondria, and thus mitochondrial DNA, are passed exclusively from mother to offspring through the egg cell. Illustration of the location of mitochondrial DNA in human cells.
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