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In 2023, the first drug making use of CRISPR gene editing, Casgevy, was approved for use in the United Kingdom to cure sickle-cell disease and beta thalassemia. [ 13 ] [ 14 ] Casgevy was approved for use in the United States on December 8, 2023, by the Food and Drug Administration .
SCell [124] integrated analysis of single-cell RNA-seq data. Seurat [125] [126] R package designed for QC, analysis, and exploration of single-cell RNA-seq data. Sincell [127] an R/Bioconductor package for statistical assessment of cell-state hierarchies from single-cell RNA-seq. SINCERA [128] A Pipeline for Single-Cell RNA-Seq Profiling Analysis.
Sickle-cell anemia, which can cause blood cells to clump up and block blood vessels, can also lead to stroke. Stroke is the second leading cause of death in people under 20 with sickle-cell anemia. [52] Air pollution may also increase stroke risk. [53]
A liquid-crystal display (LCD) is a flat-panel display or other electronically modulated optical device that uses the light-modulating properties of liquid crystals combined with polarizers. Liquid crystals do not emit light directly [1] but instead use a backlight or reflector to produce images in color or monochrome.
Budget. $18.5 million. Box office. $131.1–183.3 million. Aliens is a 1986 science fiction action film written and directed by James Cameron. It is the sequel to the 1979 science fiction horror film Alien, and the second film in the Alien franchise. Set in the far future, it stars Sigourney Weaver as Ellen Ripley, the sole survivor of an alien ...
Saxony has a long history as a duchy, an electorate of the Holy Roman Empire (the Electorate of Saxony), and finally as a kingdom (the Kingdom of Saxony).In 1918, after Germany's defeat in World War I, its monarchy was overthrown and a republican form of government was established under the current name.
Scopolamine, also known as hyoscine, [9] or Devil's Breath, [10] is a natural or synthetically produced tropane alkaloid and anticholinergic drug that is used as a medication to treat motion sickness [11] and postoperative nausea and vomiting. [12][1] It is also sometimes used before surgery to decrease saliva. [1]
Cody Garrett Runnels Rhodes (born Cody Garrett Runnels; June 30, 1985) is an American professional wrestler and actor. He is currently signed to WWE, where he performs on the SmackDown brand, and is the current Undisputed WWE Champion, recognized as both the WWE Champion and WWE Universal Champion in his first reign.