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The intravenous dose causing 50% of opioid-naive experimental subjects to die (LD 50) is "3 mg/kg in rats, 1 mg/kg in cats, 14 mg/kg in dogs, and 0.03 mg/kg in monkeys." [ 96 ] The LD 50 in mice has been given as 6.9 mg/kg by intravenous administration, 17.5 mg/kg intraperitoneally, 27.8 mg/kg by oral administration. [ 97 ]
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Grand Theft Auto V is a 2013 action-adventure game developed by Rockstar North and published by Rockstar Games.It is the seventh main entry in the Grand Theft Auto series, following 2008's Grand Theft Auto IV, and the fifteenth instalment overall.
In contrast, on 7 October 2008, Danske Bank wrote off a substantial sum largely due to property-related losses incurred by its Irish subsidiary – National Irish Bank. [117] The 3.18% [ 118 ] charge against the loan book of its Irish operations is the first significant write off to take place and is a modest indication of the extent of the ...