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  2. Sickle Cell Anemia, a Molecular Disease - Wikipedia

    en.wikipedia.org/wiki/Sickle_Cell_Anemia,_a...

    Sickle Cell Anemia, a Molecular Disease" is a 1949 scientific paper by Linus Pauling, Harvey A. Itano, Seymour J. Singer and Ibert C. Wells that established sickle-cell anemia as a genetic disease in which affected individuals have a different form of the metalloprotein hemoglobin in their blood.

  3. Hereditary persistence of fetal hemoglobin - Wikipedia

    en.wikipedia.org/wiki/Hereditary_persistence_of...

    In persons with sickle cell disease, high levels of fetal hemoglobin as found in a newborn or as found abnormally in persons with hereditary persistence of fetal hemoglobin, the HbF causes the sickle cell disease to be less severe. In essence the HbF inhibits polymerization of HbS. A similar mechanism occurs with persons who have sickle cell trait.

  4. Tiki Barber - Wikipedia

    en.wikipedia.org/wiki/Tiki_Barber

    Atiim Kiambu Hakeem-Ah "Tiki" Barber Sr [1] (/ ˈ t iː k i /; born April 7, 1975) is an American former professional football running back who spent his entire 10-year career with the New York Giants of the National Football League (NFL).

  5. Category:People with sickle-cell disease - Wikipedia

    en.wikipedia.org/wiki/Category:People_with...

    This is a non-diffusing parent category of Category:Deaths from sickle-cell disease The contents of that subcategory can also be found within this category, or in diffusing subcategories of it. Subcategories

  6. Human genetic resistance to malaria - Wikipedia

    en.wikipedia.org/wiki/Human_genetic_resistance...

    Sickle-cell disease was the genetic disorder to be linked to a mutation of a specific protein. Pauling introduced his fundamentally important concept of sickle cell anemia as a genetically transmitted molecular disease. [20] This vein (4) shows the interaction between the malaria sporozoites (6) with sickle cells (3) and regular cells (1).

  7. Colony of Virginia - Wikipedia

    en.wikipedia.org/wiki/Colony_of_Virginia

    The Colony of Virginia was a British, colonial settlement in North America between 1606 and 1776.. The first effort to create an English settlement in the area was chartered in 1584 and established in 1585; the resulting Roanoke Colony lasted for three attempts totaling six years.

  8. Asplenia - Wikipedia

    en.wikipedia.org/wiki/Asplenia

    Acquired asplenia occurs for several reasons: . Following splenectomy due to splenic rupture from trauma or because of tumor; After splenectomy with the goal of interfering with splenic function, as a treatment for diseases (e.g. idiopathic thrombocytopenic purpura, thalassemia, spherocytosis), in which the spleen's usual activity exacerbates the disease

  9. Presidency of Richard Nixon - Wikipedia

    en.wikipedia.org/wiki/Presidency_of_Richard_Nixon

    [114] [115] The second initiative, focused on Sickle-cell disease (SCD), resulted in passage of the National Sickle Cell Anemia Control Act in May 1972. Long ignored, the lifting of SCD from obscurity to high visibility reflected the changing dynamics of electoral politics and race relations in America during the early 1970s.