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Florida (/ ˈ f l ɒr ɪ d ə / ⓘ FLORR-ih-də, Spanish:) is a state in the Southeastern region of the United States.It borders the Gulf of Mexico to the west, Alabama to the northwest, Georgia to the north, the Atlantic Ocean to the east, and the Straits of Florida and Cuba to the south.
Sildenafil, sold under the brand name Viagra, among others, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. [4][8] It is also sometimes used off-label for the treatment of certain symptoms in secondary Raynaud's phenomenon. [9]
The intravenous dose causing 50% of opioid-naive experimental subjects to die (LD 50) is "3 mg/kg in rats, 1 mg/kg in cats, 14 mg/kg in dogs, and 0.03 mg/kg in monkeys." [ 96 ] The LD 50 in mice has been given as 6.9 mg/kg by intravenous administration, 17.5 mg/kg intraperitoneally, 27.8 mg/kg by oral administration. [ 97 ]