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  2. Sickle cell disease - Wikipedia

    en.wikipedia.org/wiki/Sickle_cell_disease

    Sickle cell disease (SCD), also simply called sickle cell, is a group of hemoglobin-related blood disorders typically inherited. The most common type is known as sickle cell anemia. It results in an abnormality in the oxygen-carrying protein haemoglobin found in red blood cells.

  3. Sickle cell trait - Wikipedia

    en.wikipedia.org/wiki/Sickle_cell_trait

    Sickle cell trait describes a condition in which a person has one abnormal allele of the hemoglobin beta gene (is heterozygous), but does not display the severe symptoms of sickle cell disease that occur in a person who has two copies of that allele (is homozygous).

  4. Vaso-occlusive crisis - Wikipedia

    en.wikipedia.org/wiki/Vaso-occlusive_crisis

    A vaso-occlusive crisis is a common painful complication of sickle cell anemia in adolescents and adults. [1] [2] It is a form of sickle cell crisis. Sickle cell anemia – most common in those of African, Hispanic, and Mediterranean origin – leads to sickle cell crisis when the circulation of blood vessels is obstructed by sickled red blood ...

  5. U.S. approves two sickle cell gene therapies, which doctors ...

    www.aol.com/news/u-approves-two-sickle-cell...

    Sickle cell disease is a rare, debilitating and life-threatening blood disorder with significant unmet need,” the FDA’s Dr. Nicole Verdun said in a statement announcing the approvals.

  6. Osteomyelitis - Wikipedia

    en.wikipedia.org/wiki/Osteomyelitis

    Osteomyelitis ( OM) is an infection of bone. [1] Symptoms may include pain in a specific bone with overlying redness, fever, and weakness. [1] The long bones of the arms and legs are most commonly involved in children e.g. the femur and humerus, [7] while the feet, spine, and hips are most commonly involved in adults.

  7. Asplenia - Wikipedia

    en.wikipedia.org/wiki/Asplenia

    Asplenia. Specialty. Medical genetics. Asplenia refers to the absence of normal spleen function and is associated with some serious infection risks. Hyposplenism is used to describe reduced ('hypo-') splenic functioning, but not as severely affected as with asplenism. Functional asplenia occurs when splenic tissue is present but does not work ...

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