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Sickle cell disease (SCD), also simply called sickle cell, is a group of hemoglobin-related blood disorders typically inherited. [2] The most common type is known as sickle cell anemia. [2] It results in an abnormality in the oxygen-carrying protein haemoglobin found in red blood cells. [2] This leads to a rigid, sickle -like shape under ...
Genetics is the study of genes, genetic variation, and heredity in organisms. [1][2][3] It is an important branch in biology because heredity is vital to organisms' evolution. Gregor Mendel, a Moravian Augustinian friar working in the 19th century in Brno, was the first to study genetics scientifically.
Hemoglobin S (α 2 β S 2) – A variant form of hemoglobin found in people with sickle cell disease. There is a variation in the β-chain gene, causing a change in the properties of hemoglobin, which results in sickling of red blood cells.
Malaria is a mosquito-borne infectious disease that affects vertebrates. [6][7][3] Human malaria causes symptoms that typically include fever, fatigue, vomiting, and headaches. [1][8] In severe cases, it can cause jaundice, seizures, coma, or death. [1][9] Symptoms usually begin 10 to 15 days after being bitten by an infected Anopheles mosquito ...
More often than not, disputing medical bills can reveal errors and potentially lead to a more affordable bill, according to a study published Friday in JAMA Health Forum.
FMA. 67423. Anatomical terminology. [ edit on Wikidata] Gap junctions are membrane channels between adjacent cells that allow the direct exchange of cytoplasmic substances. [ 1 ] Substances exchanged include small molecules, substrates, and metabolites. [ 1 ] Gap junctions were first described as close appositions as other tight junctions, but ...
By way of analogy, the allele (a particular version of a gene) which causes sickle cell disease when two copies are present, also confers an adaptive advantage when one copy is present by providing resistance to malaria with non-symptomatic sickle cell trait—which is known as "heterozygote advantage".
A major cause of neuronal injury is the release of the excitatory neurotransmitter glutamate. The concentration of glutamate outside the cells of the nervous system is normally kept low by so-called uptake carriers, which are powered by the concentration gradients of ions (mainly Na +) across the cell membrane. However, stroke cuts off the ...