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Chronic diseases – such as asthma, sickle cell anemia, and diabetes mellitus – increase the risk of developing a severe form of the disease. [41] Other risk factors for severe disease include female sex, and high body mass index , [ 21 ] [ 28 ] Infection with one serotype is thought to produce lifelong immunity to that type, but only short ...
On June 18, 2017, Johnson was hospitalized at the Spring Valley Medical Center in Las Vegas, Nevada due to complications related to sickle cell anemia. He had been performing with Havoc, Ghostface Killah , Onyx , KRS-One , and Ice-T on the Art of Rap Tour in Las Vegas, and had fallen ill during a meet-and-greet with fans due to hot weather ...
Pneumonia is an inflammatory condition of the lung primarily affecting the small air sacs known as alveoli. [3] [14] Symptoms typically include some combination of productive or dry cough, chest pain, fever, and difficulty breathing. [15]
Treatment is the same as for patients with sickle cell disease. Patients may receive hydroxyurea to induce the protective effects of increased fetal hemoglobin production. . They may also benefit from blood transfusions especially during vaso-occlusive cris
It is possible for a person to have both the gene for hemoglobin S (the form associated with sickle cell anemia) and the gene for hemoglobin C; this state is called hemoglobin SC disease, and is generally more severe than hemoglobin C disease, but milder than sickle cell anemia.
Sickle-cell disease was the genetic disorder to be linked to a mutation of a specific protein. Pauling introduced his fundamentally important concept of sickle cell anemia as a genetically transmitted molecular disease. [20] This vein (4) shows the interaction between the malaria sporozoites (6) with sickle cells (3) and regular cells (1).
Sickle cell disease consists of several subtypes; however, the Haemoglobin type C (HbSC) subtype carries the gravest prognosis for sickle cell retinopathy and vision changes. [ 2 ] Regular retinal examinations can aid in early detection and treatment, thus reducing the impact of the condition and the risk of vision loss.
Autosplenectomy caused by sickle cell anemia or hyposplenism in coeliac disease [3] In patients with obstructive liver disease, lecithin cholesterol acetyltransferase activity is depressed, which increases the cholesterol-to-phospholipid ratio and produces an absolute increase in the surface area of the red cell membrane.