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Leukemia (also spelled leukaemia; pronounced / luːˈkiːmiːə / [ 1 ]loo-KEE-mee-ə) is a group of blood cancers that usually begin in the bone marrow and produce high numbers of abnormal blood cells. [ 9 ] These blood cells are not fully developed and are called blasts or leukemia cells. [ 2 ]
Trisomy 21. Down syndrome (also known by the karyotype 47,XX,+21 for females and 47,XY,+21 for males) [98] is mostly caused by a failure of the 21st chromosome to separate during egg or sperm development, known as nondisjunction. [91] As a result, a sperm or egg cell is produced with an extra copy of chromosome 21; this cell thus has 24 ...
For example, sickle-cell anemia is a human genetic disease that results from a single base difference within the coding region for the β-globin section of hemoglobin, causing a single amino acid change that changes hemoglobin's physical properties. [78]
111,000 (2015) [ 10 ] Acute lymphoblastic leukemia (ALL) is a cancer of the lymphoid line of blood cells characterized by the development of large numbers of immature lymphocytes. [ 1 ] Symptoms may include feeling tired, pale skin color, fever, easy bleeding or bruising, enlarged lymph nodes, or bone pain. [ 1 ]
Glioblastoma, previously known as glioblastoma multiforme (GBM), is the most aggressive and most common type of cancer that originates in the brain, and has a very poor prognosis for survival. [6][7][8] Initial signs and symptoms of glioblastoma are nonspecific. [1] They may include headaches, personality changes, nausea, and symptoms similar ...
In 2016, 6.7% of American Indian and Alaska Native adults reported having needs for mental health services that had been unmet in the last twelve months, compared to 5.4% of the non-Hispanic white population. 8.3% of American Indian and Alaska Native adults reported experiencing a major depressive episode in the past twelve months, whereas only ...
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a disabling chronic illness. People with ME/CFS experience profound fatigue that does not go away with rest, sleep issues, and problems with memory or concentration. Further common symptoms include dizziness, nausea and pain. [3] The hallmark symptom is a worsening of the illness ...
Type 2 diabetes (T2D), formerly known as adult-onset diabetes, is a form of diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin. [6] Common symptoms include increased thirst , frequent urination , fatigue and unexplained weight loss . [ 3 ]