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Her primary research entitled Plasma volume in normal and sickle cell pregnancies was accepted. She earned a DM in Obstetrics and Gynaecology from the University of Nottingham in June 2011. [2] She is a medical educator with a diploma from the Foundation for the Advancement of International Medical Education and Research, USA.
1949: "The Inheritance of Sickle Cell Anemia"- Published in Science 110: 64-66, this paper explored how a single gene mutation is responsible for the inheritance of sickle cell anemia. Neel's research and analysis supported the pattern of a mutation occurrence in the hemoglobin subunit β (HHB gene) which is responsible for providing ...
To determine the origins of the sickle cell disease mutation, Rotimi studied the genomes of 3,000 people. He identified that sickle cell emerged around 7,000 years ago in Africa. Rotimi joined the National Institutes of Health in 2007, where he became founding director of the Trans-NIH Center for Research on Genomics and Global Health.
Sickle cell nephropathy is a type of kidney disease associated with sickle cell disease which causes kidney complications as a result of sickling of red blood cells in the small blood vessels. The hypertonic and relatively hypoxic environment of the renal medulla , coupled with the slow blood flow in the vasa recta , favors sickling of red ...
Individuals with sickle cell–hemoglobin C (HbSC), have inherited the gene for sickle cell disease (HbS) from one parent and the gene for hemoglobin C disease (HbC) from the other parent. Since HbC does not polymerize as readily as HbS, there is less sickling in most cases.
Odame's research and clinical works are in the field of sickle cell disease, thalassemia and other hematological disorders.His work at the Centre for Global Child Health also focuses on creating a continuous partnership between clinicians and scientists globally to foster academic research and improve medical care especially in developing countries with the largest disease burden.
Manu Omar Platt (born 1980) is an American biomedical engineer serving as the director of the NIH Biomedical Engineering Technology Acceleration (BETA) center. [1] [2] He also serves as NIBIB Associate Director for Scientific Diversity, Equity and Inclusion.
CRISPR-Cas9. CRISPR gene editing (CRISPR, pronounced / ˈ k r ɪ s p ə r / "crisper", refers to "clustered regularly interspaced short palindromic repeats") is a genetic engineering technique in molecular biology by which the genomes of living organisms may be modified.
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