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Methadone, sold under the brand names Dolophine and Methadose among others, is a synthetic opioid agonist used for chronic pain and also for opioid use disorder. [7] It is used to treat chronic pain, and it is also used to treat addiction to heroin or other opioids.
[162] [163] Following a government crisis Truss announced her resignation as prime minister on 20 October [164] after 44 days in office, the shortest premiership in British history. [ 164 ] [ 165 ] Truss also oversaw the worst polling the Conservatives had ever received, with Labour polling as high as 36 per cent above the Conservatives amidst ...