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Voxelotor, sold under the brand name Oxbryta, is a medication used for the treatment of sickle cell disease. [1] [3] [4] [5] [6] Voxelotor is the first hemoglobin oxygen-affinity modulator. [7] Voxelotor has been shown to have disease-modifying potential by increasing hemoglobin levels and decreasing hemolysis indicators in sickle cell patients ...
The treatment for sickle cell anemia implicitly involves hematopoietic stem cell transplantation (HSCT). [120] This entails replacing the dysfunctional stem cells in the case with healthy bones from a well-matched donor.
December 8, 2023 at 1:19 PM. The Food and Drug Administration on Friday approved a powerful treatment for sickle cell disease, a devastating illness that affects more than 100,000 Americans,...
The independent committee is helping the FDA think through how it should evaluate a treatment called exa-cel that could potentially cure people of sickle cell disease, a painful and deadly...
Hydroxycarbamide. Hydroxycarbamide, also known as hydroxyurea, is a medication used in sickle-cell disease, essential thrombocythemia, chronic myelogenous leukemia, polycythemia vera, and cervical cancer. [3] [4] In sickle-cell disease it increases fetal hemoglobin and decreases the number of attacks. [3] It is taken by mouth.
The FDA is reviewing a new drug for sickle cell disease that uses CRISPR to edit DNA. Black patients with the disease are excited and hopeful about the treatment.
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