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  2. Kwaku Ohene-Frempong - Wikipedia

    en.wikipedia.org/wiki/Kwaku_Ohene-Frempong

    Ohene-Frempong was born on 13 March 1946 in Kukurantumi, Eastern Region, Gold Coast (now Ghana) to Kwasi Adde Ohene, a cocoa farmer, and Adwoa Odi Boafo. [1] Because Kukurantumi lacked education above the middle school level, he completed Ordinary and Advanced-level secondary school studies at Prempeh College in Kumasi, Ashanti Region, where he was also a Senior Prefect.

  3. Linus Pauling - Wikipedia

    en.wikipedia.org/wiki/Linus_Pauling

    In November 1949, Pauling, Harvey Itano, S. J. Singer and Ibert Wells published "Sickle Cell Anemia, a Molecular Disease" [64] in the journal Science. It was the first proof of a human disease being caused by an abnormal protein, and sickle cell anemia became the first disease understood at the

  4. Autosplenectomy - Wikipedia

    en.wikipedia.org/wiki/Autosplenectomy

    Autosplenectomy can occur in cases of sickle-cell disease where the misshapen cells block blood flow to the spleen, causing scarring and eventual atrophy of the organ. [2] Autosplenectomy is a rare condition that is linked to certain diseases but is not a common occurrence. It is also seen in systemic lupus erythematosus (SLE).

  5. Macrocytic anemia - Wikipedia

    en.wikipedia.org/wiki/Macrocytic_anemia

    Macrocytic anemia is not a disease in the sense of having a single pathology but, rather, is a condition. As such, it is the class name for a set of pathologies that all produce somewhat the same red blood cell abnormality. Different pathologies result in macrocytic-type anemias.

  6. Crizanlizumab - Wikipedia

    en.wikipedia.org/wiki/Crizanlizumab

    Vaso-occlusive crisis is a common and painful complication of sickle cell disease that occurs when blood circulation is obstructed by sickled red blood cells (red cells are usually round and flexible, but sometimes many red cells in a person with sickle cell anemia will become rigid and crescent-shaped due to polymerization of hemoglobin). [11]

  7. Neil Hanchard - Wikipedia

    en.wikipedia.org/wiki/Neil_Hanchard

    Hanchard's research focuses on genetic factors that can lead children to manifest especially severe symptoms of malnutrition, [6] genomics of disease progression in children with HIV and tuberculosis, and genetic factors that contribute to comorbidities in sickle cell disease. [2]

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