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(Reuters) -U.S. drugmaker Pfizer said on Wednesday it is withdrawing its sickle cell disease treatment Oxbryta from all markets where it is approved, citing risks of a painful complication and deaths.
CEO Andrew Obenshain said the latest restructuring would help support the marketing of its three gene therapies, including the recently approved sickle cell disease treatment, Lyfgenia.
Sickle cell test. A urologist might request this test for men with a higher risk of sickle cell disease. Duplex ultrasound. Sometimes called ultrasonography, this can measure blood flow in your ...
This treatment thus avoids the need for regular, costly blood transfusions. [13] [14] In December 2023, the FDA approved the first gene therapy in the US to treat patients with Sickle Cell Disease (SCD). The FDA approved two milestone treatments, Casgevy and Lyfgenia, representing the first cell-based gene therapies for the treatment of SCD. [57]
However, in systemic lupus erythematosus it is 4 to 14%, [106] and in sickle cell disease, it ranges from 20 to 40%. [107] Up to 4% of people who develop a pulmonary embolism go on to develop chronic thromboembolic disease including pulmonary hypertension. [ 40 ]
Vivek Ganapathy Ramaswamy (/ v ɪ ˈ v eɪ k r ɑː m ə ˈ s w ɑː m iː /; [1] [2] vih-VAYK rah-mə-SWAH-mee; born August 9, 1985) is an American entrepreneur.He founded Roivant Sciences, a pharmaceutical company, in 2014.
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