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Sickle cell disease symptoms can include severe anemia, and infection, and debilitating pain, according to pediatric physician Matthew Heeney.
Reticulocytosis. Reticulocyte. Specialty. Hematology. Reticulocytosis is a condition where there is an increase in reticulocytes, immature red blood cells. It is commonly seen in anemia. They are seen on blood films when the bone marrow is highly active in an attempt to replace red blood cell loss such as in haemolytic anaemia or haemorrhage.
In sickle cell disease, repeated splenic infarctions lead to a non-functional spleen (autosplenectomy). Any factor that directly compromises the splenic artery can cause infarction. Examples include abdominal traumas, aortic dissection , torsion of the splenic artery (for example, in wandering spleen ) or external compression on the artery by a ...
Sick cell syndrome is a medical condition characterised by reduced functioning of the cellular Na+/K+ pump, [1] which is responsible for maintaining the internal ion homeostasis. The clinical result is a rise in blood K+ level and drop of blood Na+ levels. There are a wide range of possible pathological conditions that can cause sick cell ...
Hematology. Diamond–Blackfan anemia ( DBA) is a congenital erythroid aplasia that usually presents in infancy. [3] DBA causes low red blood cell counts ( anemia ), without substantially affecting the other blood components (the platelets and the white blood cells ), which are usually normal. This is in contrast to Shwachman–Bodian–Diamond ...
2.36 billion / 33% (2015) [2] Anemia or anaemia ( British English) is a blood disorder in which the blood has a reduced ability to carry oxygen. This can be due to a lower than normal number of red blood cells, a reduction in the amount of hemoglobin available for oxygen transport, or abnormalities in hemoglobin that impair its function.
Methemoglobinemia. Methemoglobinemia, or methaemoglobinaemia, is a condition of elevated methemoglobin in the blood. [2] Symptoms may include headache, dizziness, shortness of breath, nausea, poor muscle coordination, and blue-colored skin (cyanosis). [2] Complications may include seizures and heart arrhythmias.
Spherocytosis is the presence of spherocytes in the blood, i.e. erythrocytes ( red blood cells) that are sphere-shaped rather than bi-concave disk shaped as normal. Spherocytes are found in all hemolytic anemias to some degree. Hereditary spherocytosis and autoimmune hemolytic anemia are characterized by having only spherocytes.
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