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  2. Sickle cell disease - Wikipedia

    en.wikipedia.org/wiki/Sickle_cell_disease

    Sickle cell disease (SCD), also simply called sickle cell, is a group of hemoglobin-related blood disorders typically inherited. [2] The most common type is known as sickle cell anemia. [2] It results in an abnormality in the oxygen-carrying protein haemoglobin found in red blood cells. [2] This leads to a rigid, sickle -like shape under ...

  3. Sickle Cell Anemia, a Molecular Disease - Wikipedia

    en.wikipedia.org/wiki/Sickle_Cell_Anemia,_a...

    Sickle Cell Anemia, a Molecular Disease. " Sickle Cell Anemia, a Molecular Disease " is a 1949 scientific paper by Linus Pauling, Harvey A. Itano, Seymour J. Singer and Ibert C. Wells that established sickle-cell anemia as a genetic disease in which affected individuals have a different form of the metalloprotein hemoglobin in their blood.

  4. Sickle Cell Disease Association of America - Wikipedia

    en.wikipedia.org/wiki/Sickle_Cell_Disease...

    The Sickle Cell Disease Association of America, Inc. originated in Racine, Wisconsin. Representatives from 15 different community-based sickle cell organizations came together at Wingspread, a community center, as guest of the Johnson Foundation. There was a common belief that there was a need for national attention to sickle cell disease.

  5. She was told she wouldn’t live past her 8th birthday. Now ...

    www.aol.com/news/she-told-she-wouldn-t-110110965...

    Sickle cell is an inherited and debilitating blood disorder that causes normal round red blood cells – which carry oxygen through the body – to become crescent-shaped and rigid.

  6. FDA approves cure for sickle cell disease, the first ... - AOL

    www.aol.com/news/fda-approves-cure-sickle-cell...

    December 8, 2023 at 1:19 PM. The Food and Drug Administration on Friday approved a powerful treatment for sickle cell disease, a devastating illness that affects more than 100,000 Americans, the ...

  7. FDA advisers review sickle cell treatment that could cure the ...

    www.aol.com/fda-advisers-review-sickle-cell...

    Because of a gene mutation, sickle cell anemia causes those red blood cells to break down early — taking a sickle or c-shape that carries less oxygen. It can lead to blocked blood flow, pain ...

  8. James V. Neel - Wikipedia

    en.wikipedia.org/wiki/James_V._Neel

    1949: "The Inheritance of Sickle Cell Anemia"- Published in Science 110: 64-66, this paper explored how a single gene mutation is responsible for the inheritance of sickle cell anemia. Neel's research and analysis supported the pattern of a mutation occurrence in the hemoglobin subunit β (HHB gene) which is responsible for providing ...

  9. Harvey Itano - Wikipedia

    en.wikipedia.org/wiki/Harvey_Itano

    A Rapid Diagnostic Test for Sickle Cell Anemia (1950) Harvey Akio Itano (Japanese: ハーベイ・アキオ・イタノ[1], November 3, 1920 – May 8, 2010) was an American biochemist best known for his work on the molecular basis of sickle cell anemia and other diseases. In collaboration with Linus Pauling, Itano used electrophoresis to ...

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