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  2. Sickle cell disease - Wikipedia

    en.wikipedia.org/wiki/Sickle_cell_disease

    Sickle cell disease (SCD), also simply called sickle cell, is a group of hemoglobin-related blood disorders typically inherited. [2] The most common type is known as sickle cell anemia. [2] It results in an abnormality in the oxygen-carrying protein haemoglobin found in red blood cells. [2] This leads to a rigid, sickle -like shape under ...

  3. Sickle cell trait - Wikipedia

    en.wikipedia.org/wiki/Sickle_cell_trait

    Hematology. Sickle cell trait describes a condition in which a person has one abnormal allele of the hemoglobin beta gene (is heterozygous), but does not display the severe symptoms of sickle cell disease that occur in a person who has two copies of that allele (is homozygous). Those who are heterozygous for the sickle cell allele produce both ...

  4. FDA approves cure for sickle cell disease, the first ... - AOL

    www.aol.com/news/fda-approves-cure-sickle-cell...

    December 8, 2023 at 1:19 PM. The Food and Drug Administration on Friday approved a powerful treatment for sickle cell disease, a devastating illness that affects more than 100,000 Americans, the ...

  5. FDA approves two gene therapies for sickle cell, bringing ...

    www.aol.com/fda-expected-approve-first-crispr...

    The US Food and Drug Administration on Friday approved two gene-based treatments for sickle cell disease, including the first therapy that uses the gene-editing technique CRISPR, opening a new era ...

  6. U.S. approves two sickle cell gene therapies, which doctors ...

    www.aol.com/news/u-approves-two-sickle-cell...

    The two gene therapies are the first approved in the U.S. for sickle cell disease. The FDA has previously OK’d 15 gene therapies for other conditions. In the U.S., an estimated 100,000 people ...

  7. Sickle Cell Disease Association of America - Wikipedia

    en.wikipedia.org/wiki/Sickle_Cell_Disease...

    The Sickle Cell Disease Association of America, Inc. originated in Racine, Wisconsin. Representatives from 15 different community-based sickle cell organizations came together at Wingspread, a community center, as guest of the Johnson Foundation. There was a common belief that there was a need for national attention to sickle cell disease.

  8. Balancing selection - Wikipedia

    en.wikipedia.org/wiki/Balancing_selection

    A well-studied case is that of sickle cell anemia in humans, a hereditary disease that damages red blood cells. Sickle cell anemia is caused by the inheritance of an allele (HgbS) of the hemoglobin gene from both parents. In such individuals, the hemoglobin in red blood cells is extremely sensitive to oxygen deprivation, which results in ...

  9. FDA approves gene therapy for sickle cell disease: 'One ... - AOL

    www.aol.com/fda-approves-gene-therapy-sickle...

    Now, 33, Stephenson was one of the first to receive sickle cell gene therapy in a clinical trial six years ago. Before the treatment, Stephenson lived her life on a razor's edge.