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  2. Transfusion therapy (Sickle-cell disease) - Wikipedia

    en.wikipedia.org/wiki/Transfusion_therapy...

    Indications for red blood cell transfusion. Transfusion therapy for sickle-cell disease entails the use of red blood cell transfusions in the management of acute cases of sickle cell disease and as a prophylaxis to prevent complications by decreasing the number of red blood cells (RBC) that can sickle by adding normal red blood cells.

  3. Acute chest syndrome - Wikipedia

    en.wikipedia.org/wiki/Acute_chest_syndrome

    The crisis is a common complication in sickle-cell patients and can be associated with one or more symptoms including fever, cough, excruciating pain, sputum production, shortness of breath, or low oxygen levels. [2]

  4. Vaso-occlusive crisis - Wikipedia

    en.wikipedia.org/wiki/Vaso-occlusive_crisis

    A vaso-occlusive crisis is a common painful complication of sickle cell anemia in adolescents and adults. [1] [2] It is a form of sickle cell crisis.Sickle cell anemia – most common in those of African, Hispanic, and Mediterranean origin – leads to sickle cell crisis when the circulation of blood vessels is obstructed by sickled red blood cells, causing ischemic injuries.

  5. Sickle Cell Anemia, a Molecular Disease - Wikipedia

    en.wikipedia.org/wiki/Sickle_Cell_Anemia,_a...

    "Sickle Cell Anemia, a Molecular Disease" is a 1949 scientific paper by Linus Pauling, Harvey A. Itano, Seymour J. Singer and Ibert C. Wells that established sickle-cell anemia as a genetic disease in which affected individuals have a different form of the metalloprotein hemoglobin in their blood.

  6. Supacell - Wikipedia

    en.wikipedia.org/wiki/Supacell

    The series explores themes such as knife crime, racial profiling, poverty, the exploitation of black bodies, and sickle cell disease. Supacell received highly positive reviews from critics and audiences for its performances, direction, writing, cinematography, and visual effects, and for raising awareness of sickle cell disease. Upon its ...

  7. Exagamglogene autotemcel - Wikipedia

    en.wikipedia.org/wiki/Exagamglogene_autotemcel

    In the UK, exagamglogene autotemcel is indicated for the treatment of transfusion-dependent beta thalassemia and sickle cell disease in patients aged 12 years and older who should be treated with hematopoietic stem cell transplantation but for whom a suitable stem cell donor is not available.

  8. Pleiotropy - Wikipedia

    en.wikipedia.org/wiki/Pleiotropy

    Photomicrograph of normal-shaped and sickle-shape red blood cells from a patient with sickle cell disease. Sickle cell anemia is a genetic disease that causes deformed red blood cells with a rigid, crescent shape instead of the normal flexible, round shape. [29] It is caused by a change in one nucleotide, a point mutation [30] in the HBB gene.

  9. Prodigy (rapper) - Wikipedia

    en.wikipedia.org/wiki/Prodigy_(rapper)

    On June 18, 2017, Johnson was hospitalized at the Spring Valley Medical Center in Las Vegas, Nevada due to complications related to sickle cell anemia. He had been performing with Havoc, Ghostface Killah , Onyx , KRS-One , and Ice-T on the Art of Rap Tour in Las Vegas, and had fallen ill during a meet-and-greet with fans due to hot weather ...