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  2. Sickle cell disease - Wikipedia

    en.wikipedia.org/wiki/Sickle_cell_disease

    All the major organs are affected by sickle cell disease. The liver, heart, kidneys, gallbladder, eyes, bones, and joints also can suffer damage from the abnormal functions of the sickle cells, and their inability to flow through the small blood vessels correctly.

  3. Sickle cell trait - Wikipedia

    en.wikipedia.org/wiki/Sickle_cell_trait

    Sickle cell anemia affects about 72,000 people in the United States. Most Americans who have sickle cell anemia are of African descent. The disease also affects Americans from the Caribbean, Central America, and parts of South America, Turkey, Greece, Italy, the Middle East and East India.

  4. Heterozygote advantage - Wikipedia

    en.wikipedia.org/wiki/Heterozygote_advantage

    Sickle-cell anemia. Sickle-cell anemia (SCA) is a genetic disorder caused by the presence of two incompletely recessive alleles. When a sufferer's red blood cells are exposed to low-oxygen conditions, the cells lose their healthy round shape and become sickle-shaped. This deformation of the cells can cause them to become lodged in capillaries ...

  5. Watch: Why does sickle cell affect Black people at a ... - AOL

    www.aol.com/news/watch-why-does-sickle-cell...

    The post Watch: Why does sickle cell affect Black people at a higher rate? appeared first on TheGrio. Tevin and Akilah Coleman and Dr. Kim Smith-Whitley are helping to bring awareness to sickle ...

  6. Sickle Cell Disease Association of America - Wikipedia

    en.wikipedia.org/wiki/Sickle_Cell_Disease...

    Beverley Francis-Gibson. Website. www.sicklecelldisease.org. The Sickle Cell Disease Association of America, Inc. ( SCDAA) is a nonprofit organization with the sole purpose of supporting research, education and funding of individuals, families those who are impacted by sickle cell disease .

  7. Vaso-occlusive crisis - Wikipedia

    en.wikipedia.org/wiki/Vaso-occlusive_crisis

    It is a form of sickle cell crisis. Sickle cell anemia – most common in those of African, Hispanic, and Mediterranean origin – leads to sickle cell crisis when the circulation of blood vessels is obstructed by sickled red blood cells, causing ischemic injuries.

  8. Elizabeth Anionwu - Wikipedia

    en.wikipedia.org/wiki/Elizabeth_Anionwu

    With the help of Professor Marcus Pembrey, Anionwu taught a course at University College London for National Health Service (NHS) staff members who worked with communities affected or at risk of sickle-cell disease, cystic fibrosis, TaySachs disease and thalassaemia .

  9. Mendelian traits in humans - Wikipedia

    en.wikipedia.org/wiki/Mendelian_traits_in_humans

    Mendelian traits in humans. Autosomal dominant. A 50/50 chance of inheritance. Sickle-cell disease is inherited in the autosomal recessive pattern. When both parents have sickle-cell trait (carrier), a child has a 25% chance of sickle-cell disease (red icon), 25% do not carry any sickle-cell alleles (blue icon), and 50% have the heterozygous ...

  10. Sickle cell retinopathy - Wikipedia

    en.wikipedia.org/wiki/Sickle_cell_retinopathy

    People affected by sickle cell disease are commonly of African or Asian descent. Emigration patterns towards the Western Hemisphere have led to increased numbers of persons affected by sickle cell disease in regions where it was previously uncommon.

  11. Acute chest syndrome - Wikipedia

    en.wikipedia.org/wiki/Acute_chest_syndrome

    The acute chest syndrome is a vaso-occlusive crisis of the pulmonary vasculature commonly seen in people with sickle cell anemia. This condition commonly manifests with a new opacification of the lung(s) on a chest x-ray .