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Sickle cell anemia. An example of overdominance in humans is that of the sickle cell anemia. This condition is determined by a single polymorphism. Possessors of the deleterious allele have lower life expectancy, with homozygotes rarely reaching 50 years of age. However, this allele also yields some resistance to malaria. Thus in regions where ...
Ryan Terry Clark [1] [2] (born October 12, 1979) is an American former professional football player who was a safety in the National Football League (NFL). He played college football for the LSU Tigers, and was signed by the New York Giants as an undrafted free agent in 2002. Clark also played for the Pittsburgh Steelers and for the Washington ...
Mendelian traits in humans. A 50/50 chance of inheritance. Sickle-cell disease is inherited in the autosomal recessive pattern. When both parents have sickle-cell trait (carrier), a child has a 25% chance of sickle-cell disease (red icon), 25% do not carry any sickle-cell alleles (blue icon), and 50% have the heterozygous (carrier) condition. [1]
On June 20, 2017, it was reported that Prodigy had died at the Spring Valley Medical Center in Las Vegas, Nevada, while hospitalized for complications related to his sickle-cell anemia. He was performing in the Art of Rap Tour in Las Vegas with Havoc, Ghostface Killah , Onyx , KRS-One , and Ice-T when he was hospitalized.
Haemophilia figured prominently in the history of European royalty in the 19th and 20th centuries. Queen Victoria and her husband, Prince Albert, of the United Kingdom, through two of their five daughters – Princess Alice and Princess Beatrice – passed the mutation to various royal houses across the continent, including the royal families ...
Genetic disorder. A genetic disorder is a health problem caused by one or more abnormalities in the genome. It can be caused by a mutation in a single gene (monogenic) or multiple genes (polygenic) or by a chromosomal abnormality. Although polygenic disorders are the most common, the term is mostly used when discussing disorders with a single ...
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