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The intravenous dose causing 50% of opioid-naive experimental subjects to die (LD 50) is "3 mg/kg in rats, 1 mg/kg in cats, 14 mg/kg in dogs, and 0.03 mg/kg in monkeys." [ 96 ] The LD 50 in mice has been given as 6.9 mg/kg by intravenous administration, 17.5 mg/kg intraperitoneally, 27.8 mg/kg by oral administration. [ 97 ]
At the conclusion of its sixth rate-setting policy meeting of 2024 on September 18, 2024, the Federal Reserve announced it was lowering the federal funds target interest rate by 50 basis points to ...
Christian of Brunswick. The Thirty Years' War, [ j ] from 1618 to 1648, was one of the most destructive conflicts in European history. Fought primarily in Central Europe, an estimated 4.5 to 8 million soldiers and civilians died from the effects of battle, famine, or disease, while parts of Germany reported population declines of over 50%. [ 19 ]
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