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The intravenous dose causing 50% of opioid-naive experimental subjects to die (LD 50) is "3 mg/kg in rats, 1 mg/kg in cats, 14 mg/kg in dogs, and 0.03 mg/kg in monkeys." [ 96 ] The LD 50 in mice has been given as 6.9 mg/kg by intravenous administration, 17.5 mg/kg intraperitoneally, 27.8 mg/kg by oral administration. [ 97 ]
The 2021–22 NBA season was the 76th season of the National Basketball Association (NBA). The regular season began on October 19, 2021, and ended on April 10, 2022. [1] For the first time since the 2018–19 season, the NBA returned to its usual October to April regular season schedule after the previous two seasons were shortened due to the COVID-19 pandemic.
At the conclusion of its sixth rate-setting policy meeting of 2024 on September 18, 2024, the Federal Reserve announced it was lowering the federal funds target interest rate by 50 basis points to ...
[128] [129] In 2021, it was estimated that the population of oceanic sharks and rays had dropped by 71% over the previous half-century. [ 7 ] Shark finning yields are estimated at 1.44 million metric tons (1.59 million short tons) for 2000, and 1.41 million metric tons (1.55 million short tons) for 2010.
Christian of Brunswick. The Thirty Years' War, [ j ] from 1618 to 1648, was one of the most destructive conflicts in European history. Fought primarily in Central Europe, an estimated 4.5 to 8 million soldiers and civilians died from the effects of battle, famine, or disease, while parts of Germany reported population declines of over 50%. [ 19 ]
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