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Lovotibeglogene autotemcel, sold under the brand name Lyfgenia, is a lentiviral gene therapy used for the treatment of sickle cell disease. [1] [3] [4] [5]The most common side effects include stomatitis (mouth sores of the lips, mouth, and throat), low levels of platelets, white blood cells, and red blood cells, and febrile neutropenia (fever and low white blood cell count), consistent with ...
The acute chest syndrome is a vaso-occlusive crisis of the pulmonary vasculature commonly seen in people with sickle cell anemia. This condition commonly manifests with a new opacification of the lung(s) on a chest x-ray .
In people with sickle-cell disease or other forms of chronic hemolytic anemia, a blood disorder, the infection can precipitate an aplastic crisis, wherein the bone marrow of the individual will suddenly stop producing red blood cells. [1] [2] A 2019 systematic review examined the rates of parvovirus B19 infection among daycare workers.
T-Boz opened up to the public about the disease in 1996; [26] she later became one of the spokespersons for Sickle Cell Disease Association of America. [27] [28] In 2002, she was hospitalized for four months due to a flare-up of sickle-cell anemia. [29] She is a national co-chair of the progressive organization Health Care Voter. [30]
Goals are to increase public awareness about dengue, mobilize resources for its prevention and control and, to demonstrate the Southeast Asian region's commitment in tackling the disease. [92] Efforts are ongoing as of 2019 to make it a global event. [93] The Philippines has an awareness month in June since 1998. [94] [95]
Newborn screening programs initially used screening criteria based largely on criteria established by JMG Wilson and F. Jungner in 1968. [6] Although not specifically about newborn population screening programs, their publication, Principles and practice of screening for disease proposed ten criteria that screening programs should meet before being used as a public health measure.
Pneumonia is an inflammatory condition of the lung primarily affecting the small air sacs known as alveoli. [3] [14] Symptoms typically include some combination of productive or dry cough, chest pain, fever, and difficulty breathing. [15]
His description of the student's disease was known for many years as Herrick's syndrome, and is now known as sickle-cell disease. The condition is prevalent in West Africa . Herrick's second major contribution was a landmark article on myocardial infarction ("heart attack") in JAMA in 1912.