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Ketoconazole is a racemic mixture consisting of cis-(2S,4R)-(−) and cis-(2R,4S)-(+) enantiomers. [10] The cis -(2 S ,4 R ) isomer was more potent in inhibiting progesterone 17α,20-lyase than its enantiomer ( IC 50 values of 0.05 and 2.38 μ M, respectively) and in inhibiting 11β-hydroxylase (IC 50 values of 0.152 and 0.608 μ M, respectively).
Keratosis pilaris. Keratosis pilaris (KP; also follicular keratosis, lichen pilaris, or colloquially chicken skin[1]) is a common, autosomal - dominant, genetic condition of the skin's hair follicles characterized by the appearance of possibly itchy, small, gooseflesh -like bumps, with varying degrees of reddening or inflammation. [2]
The topical cream is indicated for treatment of facial hirsutism in women. [1] [18] It is the only topical prescription treatment that slows the growth of facial hair. [19] In clinical studies with Vaniqa, 81% percent of women showed clinical improvement after twelve months of treatment. [20] Positive results were seen after eight weeks. [21]
Dandruff. Dandruff is a skin condition that mainly affects the scalp. [1] Symptoms include flaking and sometimes mild itchiness. [1][2] It can result in social or self-esteem problems. [4] A more severe form of the condition, which includes inflammation of the skin, is known as seborrhoeic dermatitis. [1] The cause is unclear, but believed to ...
Telogen effluvium. Telogen effluvium is a scalp disorder characterized by the thinning or shedding of hair resulting from the early entry of hair in the telogen phase (the resting phase of the hair follicle). [1][2] It is in this phase that telogen hairs begin to shed at an increased rate, where normally the approximate rate of hair loss ...
Common side effects when used as a cream are limited to the skin and include skin redness, peeling, and sun sensitivity. [10] When taken by mouth, side effects include hypertriglyceridemia, hypercholesterolemia, shortness of breath, headache, numbness, depression, skin dryness, itchiness, hair loss, vomiting, muscle pains, and vision changes. [8]
Folliculitis keloidalis scarring on the nape of the neck is most common among males with curly hair. Oil folliculitis is inflammation of hair follicles due to exposure to various oils, and typically occurs on forearms or thighs. It is common in refinery workers, road workers, mechanics, and sheep shearers. Even makeup may cause it.
But those chemicals are in many products, so just avoiding them in sunscreen is "probably not making a big difference," Waldman adds. Similarly, He discusses the data with pregnant patients who ...