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  2. Human genetic resistance to malaria - Wikipedia

    en.wikipedia.org/wiki/Human_genetic_resistance...

    Sickle-cell disease was the genetic disorder to be linked to a mutation of a specific protein. Pauling introduced his fundamentally important concept of sickle cell anemia as a genetically transmitted molecular disease. [20] This vein (4) shows the interaction between the malaria sporozoites (6) with sickle cells (3) and regular cells (1).

  3. Newborn screening - Wikipedia

    en.wikipedia.org/wiki/Newborn_screening

    In the United States, newborn screening for sickle cell disease was recommended for all infants in 1987, however it was not implemented in all 50 states until 2006. [22] Early identification of individuals with sickle cell disease and other hemoglobinopathies allows treatment to be initiated in a timely fashion.

  4. Sickle cell nephropathy - Wikipedia

    en.wikipedia.org/wiki/Sickle_cell_nephropathy

    Sickle cell nephropathy is a type of kidney disease associated with sickle cell disease which causes kidney complications as a result of sickling of red blood cells in the small blood vessels. The hypertonic and relatively hypoxic environment of the renal medulla , coupled with the slow blood flow in the vasa recta , favors sickling of red ...

  5. She was told she wouldn’t live past her 8th birthday. Now ...

    www.aol.com/news/she-told-she-wouldn-t-110110965...

    In a region that has the world’s highest rates of sickle cell, Lea Kilenga and her nonprofit are helping fellow Kenyans get crucial treatment and battling the stigma surrounding the disease.

  6. Exagamglogene autotemcel - Wikipedia

    en.wikipedia.org/wiki/Exagamglogene_autotemcel

    The treatment was approved in the United Kingdom for the treatment of sickle cell disease and transfusion-dependent beta thalassemia in November 2023. [9] [10] [11] It was approved in the United States for the treatment of sickle cell disease in December 2023 and for the treatment of transfusion-dependent beta thalassemia in January 2024. [8 ...

  7. Stephanie Edwards (Grey's Anatomy) - Wikipedia

    en.wikipedia.org/wiki/Stephanie_Edwards_(Grey's...

    Stephanie was born with sickle-cell disease. At the age of 5, she participated in a clinical trial at St. Jude Children's Research Hospital, which used bone marrow transplants to treat the disease. The treatment was highly effective for her, and Dr. Keith Wagner, who led the study, considered Stephanie one of its most successful cases.

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