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Sickle cell disease (SCD), also simply called sickle cell, is a group of hemoglobin-related blood disorders typically inherited. [2] The most common type is known as sickle cell anemia. [2] It results in an abnormality in the oxygen-carrying protein haemoglobin found in red blood cells. [2] This leads to a rigid, sickle -like shape under ...
Anemia or anaemia (British English) is a blood disorder in which the blood has a reduced ability to carry oxygen. This can be due to a lower than normal number of red blood cells, a reduction in the amount of hemoglobin available for oxygen transport, or abnormalities in hemoglobin that impair its function. [3][4]
Anemia has many different causes, although iron deficiency and its resultant iron deficiency anemia are the most common causes in the Western world. As absence of iron decreases heme synthesis, red blood cells in iron deficiency anemia are hypochromic (lacking the red hemoglobin pigment) and microcytic (smaller than normal). Other anemias are ...
The most common symptoms can be summed up in the acronym "CRAB," which stands for high calcium levels in the blood, renal (or kidney) insufficiency, anemia and bone destruction, experts say ...
Pernicious anemia is the most common cause of vitamin B 12 deficiency. [ 125 ] [ 126 ] Any disruption that leads to the loss of parietal cells can lead to malabsorption, and includes atrophic gastritis , a condition that often affects the elderly, [ 127 ] and gastric surgeries that involve the removal of all or part of the stomach, such as Roux ...
Sickle-cell anemia, which can cause blood cells to clump up and block blood vessels, can also lead to stroke. Stroke is the second leading cause of death in people under 20 with sickle-cell anemia. [52] Air pollution may also increase stroke risk. [53]
For example, sickle-cell anemia is a human genetic disease that results from a single base difference within the coding region for the β-globin section of hemoglobin, causing a single amino acid change that changes hemoglobin's physical properties. [78]
One of the most common symptoms of osteosarcoma is bone pain that lasts several weeks. This pain often begins as mild and may come and go. It usually starts in the area where the tumor is located ...