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  2. Sickle cell disease - Wikipedia

    en.wikipedia.org/wiki/Sickle_cell_disease

    Migration of substantial populations from these high-prevalence areas to low-prevalence countries in Europe has dramatically increased in recent decades and in some European countries, sickle cell disease has now overtaken more familiar genetic conditions such as haemophilia and cystic fibrosis.

  3. Global Burden of Disease Study - Wikipedia

    en.wikipedia.org/wiki/Global_Burden_of_Disease_Study

    The Global Burden of Disease Study began in 1990 as a single World Bank -commissioned [3] study that quantified the health effects of more than 100 diseases and injuries for eight regions of the world, giving estimates of morbidity and mortality by age, sex, and region. It also introduced the disability-adjusted life year (DALY) as a new metric ...

  4. Newborn screening - Wikipedia

    en.wikipedia.org/wiki/Newborn_screening

    The conditions included in newborn screening programs around the world vary greatly, based on the legal requirements for screening programs, prevalence of certain diseases within a population, political pressure, and the availability of resources for both testing and follow-up of identified patients.

  5. The world's first gene therapy for sickle cell disease has ...

    www.aol.com/news/uk-becomes-1st-country-approve...

    Britain's medicines regulator has authorized the world's first gene therapy treatment for sickle cell disease, in a move that could offer relief to thousands of people with the crippling disease ...

  6. Sickle Cell Disease Association of America - Wikipedia

    en.wikipedia.org/wiki/Sickle_Cell_Disease...

    The Sickle Cell Disease Association of America, Inc. originated in Racine, Wisconsin. Representatives from 15 different community-based sickle cell organizations came together at Wingspread, a community center, as guest of the Johnson Foundation. There was a common belief that there was a need for national attention to sickle cell disease.

  7. A rural Ugandan community is a hot spot for sickle cell ... - AOL

    www.aol.com/news/rural-ugandan-community-hot...

    The only cure for the pain sickle cell disease can cause is a bone marrow transplant or gene therapies like the one commercially approved by the U.S. Food and Drug Administration in December. A 12 ...

  8. Promising new gene therapies for sickle cell are out of ... - AOL

    www.aol.com/news/promising-gene-therapies-sickle...

    The price tags for the two sickle cell therapies in the U.S. are $3.1 million and $2.2 million although costs can vary by country. The process of giving the therapies is just as big a hurdle.

  9. Sickle Cell Anemia, a Molecular Disease - Wikipedia

    en.wikipedia.org/wiki/Sickle_Cell_Anemia,_a...

    The molecular disease concept put forward in the 1949 paper also became the basis for Linus Pauling's view of evolution. In the 1960s, by which time it had been shown that sickle cell trait confers resistance to malaria and so the gene had both positive and negative effects and demonstrated heterozygote advantage, Pauling suggested that ...

  10. Sickle cell trait - Wikipedia

    en.wikipedia.org/wiki/Sickle_cell_trait

    Sickle cell anemia affects about 72,000 people in the United States. Most Americans who have sickle cell anemia are of African descent. The disease also affects Americans from the Caribbean, Central America, and parts of South America, Turkey, Greece, Italy, the Middle East and East India.

  11. For people with sickle cell disease, ERs can mean life ... - AOL

    www.aol.com/news/people-sickle-cell-disease-ers...

    Advocates for sickle cell patients said investment in data collection to track the disease is also important. Although the Centers for Disease Control and Prevention estimates that some 100,000 ...