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  2. Sickle cell disease - Wikipedia

    en.wikipedia.org/wiki/Sickle_cell_disease

    Sickle cell disease (SCD), also simply called sickle cell, is a group of hemoglobin-related blood disorders typically inherited. The most common type is known as sickle cell anemia . [2] It results in an abnormality in the oxygen-carrying protein haemoglobin found in red blood cells . [2]

  3. Sickle cell trait - Wikipedia

    en.wikipedia.org/wiki/Sickle_cell_trait

    Sickle cell trait describes a condition in which a person has one abnormal allele of the hemoglobin beta gene (is heterozygous), but does not display the severe symptoms of sickle cell disease that occur in a person who has two copies of that allele (is homozygous).

  4. US FDA approves two gene therapies for sickle cell disease - AOL

    www.aol.com/news/us-approves-two-gene-therapies...

    (Reuters) -The U.S. Food and Drug Administration (FDA) on Friday approved two gene therapies for sickle cell disease, making one of them the first treatment in the United States based on the...

  5. U.S. approves two sickle cell gene therapies, which doctors ...

    www.aol.com/news/u-approves-two-sickle-cell...

    Regulators on Friday approved two gene therapies for sickle cell disease that doctors hope can cure the painful, inherited blood disorder that afflicts mostly Black people in the U.S.

  6. FDA approves gene therapy for sickle cell disease: 'One ... - AOL

    www.aol.com/fda-approves-gene-therapy-sickle...

    Sickle cell is the most common disease to receive approval for gene therapy treatment, following decades of development and years of approvals for therapy for people with rarer conditions.

  7. Sickle Cell Disease Association of America - Wikipedia

    en.wikipedia.org/wiki/Sickle_Cell_Disease...

    Website. www.sicklecelldisease.org. The Sickle Cell Disease Association of America, Inc. ( SCDAA) is a nonprofit organization with the sole purpose of supporting research, education and funding of individuals, families those who are impacted by sickle cell disease .

  8. FDA approves cure for sickle cell disease, the first ... - AOL

    www.aol.com/news/fda-approves-cure-sickle-cell...

    The Food and Drug Administration on Friday approved a powerful treatment for sickle cell disease, a devastating illness that affects more than 100,000 Americans, the majority of whom are Black.

  9. Pleiotropy - Wikipedia

    en.wikipedia.org/wiki/Pleiotropy

    Sickle cell anemia is a genetic disease that causes deformed red blood cells with a rigid, crescent shape instead of the normal flexible, round shape. It is caused by a change in one nucleotide, a point mutation [30] in the HBB gene .

  10. Promising new gene therapies for sickle cell are out of ... - AOL

    www.aol.com/news/promising-gene-therapies-sickle...

    New gene therapies promise a cure for sickle cell disease, and Dongre says he’s “praying the treatment should come to us.” Vast inequities cut much of the world off from gene therapy in...

  11. The world’s first gene therapy for sickle cell disease has ...

    www.aol.com/world-first-gene-therapy-sickle...

    LONDON (AP) — Britain’s medicines regulator has authorized the world’s first gene therapy treatment for sickle cell disease, in a move that could offer relief to thousands of people with the...