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[50] [51] In July 2020, the FDA approved both Fluad and Fluad Quadrivalent for use in the United States for the 2020–2021 influenza season. [ 50 ] [ 52 ] The B/Yamagata lineage of influenza B , one of the four lineages targeted by quadrivalent vaccines, might have become extinct in 2020/2021 due to COVID-19 pandemic measures, [ 53 ] and there ...
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men firing from trenches – 1/15–1/50 men crouching in trenches – 1/25–1/100 Airburst munitions significantly increase the relative risk for lying men, etc. Historically most casualties occur in the first 10–15 seconds of fire, i.e. the time needed to react and improve protective posture, however, this is less relevant if airburst is used.
The intravenous dose causing 50% of opioid-naive experimental subjects to die (LD 50) is "3 mg/kg in rats, 1 mg/kg in cats, 14 mg/kg in dogs, and 0.03 mg/kg in monkeys." [ 96 ] The LD 50 in mice has been given as 6.9 mg/kg by intravenous administration, 17.5 mg/kg intraperitoneally, 27.8 mg/kg by oral administration. [ 97 ]