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People diagnosed with sickle cell disorder are at an increased risk of blood clots and stroke, according to Miller, because the sickle-shaped red blood cells can get lodged in the bloodstream ...
Pages in category "People with sickle-cell disease" The following 16 pages are in this category, out of 16 total. This list may not reflect recent changes. A.
James B Herrick: the discoverer of sickle cell anemia. His first case report received scant interest--only in the 1950s was the role of "moon-crescent" shape considered]. Läkartidningen (in Swedish).
The Chontal Maya are a Maya people of the Mexican state of Tabasco. "Chontal", from the Nahuatl word for chontalli, which means "foreigner", has been applied to various ethnic groups in Mexico.
The sickle cell trait provides a survival advantage against malaria fatality over people with normal hemoglobin in regions where malaria is endemic. The trait is known to cause significantly fewer deaths due to malaria, especially when Plasmodium falciparum is the causative organism.
At the time it was a scientific puzzle that the disease was prevalent even though it killed people before they reached puberty, before they can have children to pass on the lethal gene. [4] He found that the prevalence of sickle-cell trait (heterozygous condition) among people inhabiting coastal areas was higher than 20%. [8]
It is possible for a person to have both the gene for hemoglobin S (the form associated with sickle cell anemia) and the gene for hemoglobin C; this state is called hemoglobin SC disease, and is generally more severe than hemoglobin C disease, but milder than sickle cell anemia. [2]
Autosplenectomy can occur in cases of sickle-cell disease where the misshapen cells block blood flow to the spleen, causing scarring and eventual atrophy of the organ. [2] Autosplenectomy is a rare condition that is linked to certain diseases but is not a common occurrence. It is also seen in systemic lupus erythematosus (SLE).