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  2. Diamond–Blackfan anemia - Wikipedia

    en.wikipedia.org/wiki/Diamond–Blackfan_anemia

    Diamond–Blackfan anemia (DBA) is a congenital erythroid aplasia that usually presents in infancy. [3] DBA causes low red blood cell counts (), without substantially affecting the other blood components (the platelets and the white blood cells), which are usually normal.

  3. Malaria - Wikipedia

    en.wikipedia.org/wiki/Malaria

    Sickle cell trait causes a change in the haemoglobin molecule in the blood. ... Although the shorter life expectancy for those with the homozygous condition would ...

  4. Hereditary spherocytosis - Wikipedia

    en.wikipedia.org/wiki/Hereditary_spherocytosis

    Hereditary spherocytosis is the heritable hemolytic disorder, affecting 1 in 2,000 people of Northern European ancestry. [5] According to Harrison's Principles of Internal Medicine, the frequency is at least 1 in 5,000 within the United States of America. [6]

  5. Cystic fibrosis - Wikipedia, the free encyclopedia

    en.wikipedia.org/wiki/Cystic_fibrosis

    Cystic fibrosis (also known as CF or mucoviscidosis) is an autosomal recessive genetic disorder affecting most critically the lungs, and also the pancreas, liver, and intestine.

  6. Down syndrome - Wikipedia

    en.wikipedia.org/wiki/Down_syndrome

    Life expectancy is around 50 to 60 years in the developed world, with proper health care. [9] [10] Regular screening for health issues common in Down syndrome is recommended throughout the person's life. [9] Down syndrome is the most common chromosomal abnormality, [25] occurring in about 1 in 1,000 babies born worldwide, [1] and one in 700 in ...

  7. Race and health in the United States - Wikipedia

    en.wikipedia.org/wiki/Race_and_health_in_the...

    While 65-year-old black men had a lower total life expectancy (11.4 years) and active life expectancy (10 years) than white men (total life expectancy, 12.6 years; active life expectancy, 11.2 years), those differences were reduced when controlling for education.

  8. Haemophilia in European royalty - Wikipedia

    en.wikipedia.org/wiki/Haemophilia_in_European...

    The rate of spontaneous mutation is known to increase with paternal age (and is higher in fathers than in mothers at all ages); Victoria's father was 51 at her birth. The probability of Victoria's mother having had a lover with haemophilia is minuscule given the low life expectancy of early 19th-century haemophiliacs.

  9. Sickle Cell Anemia, a Molecular Disease - Wikipedia

    en.wikipedia.org/wiki/Sickle_Cell_Anemia,_a...

    The paper, published in the November 25, 1949 issue of Science, reports a difference in electrophoretic mobility between hemoglobin from healthy individuals and those with sickle-cell anemia, with those with sickle cell trait having a mixture of the two types.

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