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Adapter molecule crk is a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. This protein has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction.
Pennsylvania (/ ˌ p ɛ n s ɪ l ˈ v eɪ n i ə / ⓘ, lit. ' Penn's forest country '), officially the Commonwealth of Pennsylvania (Pennsylvania Dutch: Pennsylvanie), is a state spanning the Mid-Atlantic, Northeastern, Appalachian, and Great Lakes regions of the United States.
12929 Ensembl ENSG00000099942 ENSMUSG00000006134 UniProt P46109 P47941 RefSeq (mRNA) NM_005207 NM_001277231 NM_007764 RefSeq (protein) NP_005198 NP_001264160 NP_031790 Location (UCSC) Chr 22: 20.92 – 20.95 Mb Chr 16: 17.27 – 17.31 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Crk-like protein is a protein that in humans is encoded by the CRKL gene. Function v-CRK avian sarcoma ...
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Engine is a Shay locomotive. The Georgetown Loop Railroad is a 3 ft ( 914 mm) narrow gauge United States heritage railroad located in the Rocky Mountains in Clear Creek County, adjacent to Interstate 70 in Colorado . This tourist train runs between the communities of Georgetown and Silver Plume, a distance of 2 miles (3.2 km).
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