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  2. FDA approves cure for sickle cell disease, the first ... - AOL

    www.aol.com/news/fda-approves-cure-sickle-cell...

    The Food and Drug Administration on Friday approved a powerful treatment for sickle cell disease, a devastating illness that affects more than 100,000 Americans, the majority of whom are Black ...

  3. Glucose-6-phosphate dehydrogenase deficiency - Wikipedia

    en.wikipedia.org/wiki/Glucose-6-phosphate_de...

    Most individuals with G6PD deficiency are asymptomatic.When it induces hemolysis, it is usually is short-lived. [5]Most people who develop symptoms are male, due to the X-linked pattern of inheritance, but female carriers can be affected due to unfavorable lyonization or skewed X-inactivation, where random inactivation of an X-chromosome in certain cells creates a population of G6PD-deficient ...

  4. Congenital hemolytic anemia - Wikipedia

    en.wikipedia.org/wiki/Congenital_hemolytic_anemia

    The goal of sickle cell anemia treatment is usually to avoid pain episodes, relieve symptoms, and prevent complications. Medication and blood transfusions may be used as treatments. A stem cell transplant may be able to cure the disease in some children and teenagers.

  5. Hydroxycarbamide - Wikipedia

    en.wikipedia.org/wiki/Hydroxycarbamide

    Hydroxycarbamide, also known as hydroxyurea, is a medication used in sickle-cell disease, essential thrombocythemia, chronic myelogenous leukemia, polycythemia vera, and cervical cancer. [4] [5] In sickle-cell disease it increases fetal hemoglobin and decreases the number of attacks. [4] It is taken by mouth. [4]

  6. Hemolytic anemia - Wikipedia

    en.wikipedia.org/wiki/Hemolytic_anemia

    Treatment depends on the type and cause of the hemolytic anemia. [2] Symptoms of hemolytic anemia are similar to other forms of anemia (fatigue and shortness of breath), but in addition, the breakdown of red cells leads to jaundice and increases the risk of particular long-term complications, such as gallstones [4] and pulmonary hypertension. [5]

  7. Gene therapy - Wikipedia

    en.wikipedia.org/wiki/Gene_therapy

    Clinical trials of gene therapy for sickle cell disease were started in 2014. [223] [224] In February LentiGlobin BB305, a gene therapy treatment undergoing clinical trials for treatment of beta thalassemia gained FDA "breakthrough" status after several patients were able to forgo the frequent blood transfusions usually required to treat the ...

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