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  2. Sickle cell disease - Wikipedia

    en.wikipedia.org/wiki/Sickle_cell_disease

    Sickle cell disease (SCD), also simply called sickle cell, is a group of hemoglobin-related blood disorders typically inherited. [2] The most common type is known as sickle cell anemia. [2] It results in an abnormality in the oxygen-carrying protein haemoglobin found in red blood cells. [2] This leads to a rigid, sickle -like shape under ...

  3. Anthony Clifford Allison - Wikipedia

    en.wikipedia.org/wiki/Anthony_Clifford_Allison

    Anthony Clifford Allison (21 August 1925 – 20 February 2014) was a South African geneticist and medical scientist who made pioneering studies on the genetic resistance to malaria. [2] Clark completed his primary schooling in Kenya, completed his higher education in South Africa, and obtained a BSc in medical science from the University of the ...

  4. Howell–Jolly body - Wikipedia

    en.wikipedia.org/wiki/Howell–Jolly_body

    A Howell–Jolly body is a cytopathological finding of basophilic nuclear remnants (clusters of DNA) in circulating erythrocytes. During maturation in the bone marrow, late erythroblasts normally expel their nuclei; but, in some cases, a small portion of DNA remains. The presence of Howell–Jolly bodies usually signifies a damaged or absent ...

  5. New sickle cell treatment sparks feelings of hope and some ...

    www.aol.com/news/sickle-cell-treatment-sparks...

    A 2021 analysis by NORC, an independent research organization affiliated with the University of Chicago, identified 52,524 people with sickle cell disease who were enrolled in Medicaid in 2021 and ...

  6. FDA approves two gene therapies for sickle cell, bringing ...

    www.aol.com/fda-expected-approve-first-crispr...

    For sickle cell, patients’ cells are removed from the body and CRISPR is used to make an edit that turns back on production of fetal hemoglobin, a form of the protein that babies make in the ...

  7. FDA approves cure for sickle cell disease, the first ... - AOL

    www.aol.com/news/fda-approves-cure-sickle-cell...

    December 8, 2023 at 1:19 PM. The Food and Drug Administration on Friday approved a powerful treatment for sickle cell disease, a devastating illness that affects more than 100,000 Americans, the ...

  8. Sickle cell trait - Wikipedia

    en.wikipedia.org/wiki/Sickle_cell_trait

    Hematology. Sickle cell trait describes a condition in which a person has one abnormal allele of the hemoglobin beta gene (is heterozygous), but does not display the severe symptoms of sickle cell disease that occur in a person who has two copies of that allele (is homozygous). Those who are heterozygous for the sickle cell allele produce both ...

  9. Sickle Cell Disease Association of America - Wikipedia

    en.wikipedia.org/wiki/Sickle_Cell_Disease...

    The Sickle Cell Disease Association of America, Inc. originated in Racine, Wisconsin. Representatives from 15 different community-based sickle cell organizations came together at Wingspread, a community center, as guest of the Johnson Foundation. There was a common belief that there was a need for national attention to sickle cell disease.