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Osteonecrosis is also associated with cancer, lupus, sickle cell disease, [11] HIV infection, Gaucher's disease, and Caisson disease (dysbaric osteonecrosis). [1] [12] Bisphosphonates are associated with osteonecrosis of the mandible (jawbone). [13] The condition may also occur without any clear reason. [1]
However, in people with conditions where the cells die early (such as sickle cell disease), parvovirus infection can lead to severe anemia. [15] [16] More frequently, parvovirus B19 is associated with aplastic crisis, which involves only red blood cells (despite the name). Aplastic anemia involves all cell lines.
Professor Falusi conducts research on the genetics of Sickle Cell Disease. She is currently focused on awareness and education of the public on sickle cell disease. She is a co-founder of Sickle Cell Association of Nigeria (SCAN), as well as the founder and trustee of the Sickle Cell Hope Alive Foundation.
Patients with sickle cell disease are also at high risk. ... He noted that the CDC alert was intended to raise awareness among doctors, not to concern the public.
His description of the student's disease was known for many years as Herrick's syndrome, and is now known as sickle-cell disease. The condition is prevalent in West Africa . Herrick's second major contribution was a landmark article on myocardial infarction ("heart attack") in JAMA in 1912.
Sickle Cell Anemia, a Molecular Disease" is a 1949 scientific paper by Linus Pauling, Harvey A. Itano, Seymour J. Singer and Ibert C. Wells that established sickle-cell anemia as a genetic disease in which affected individuals have a different form of the metalloprotein hemoglobin in their blood.