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Sickle cell disease (SCD), also simply called sickle cell, is a group of hemoglobin-related blood disorders typically inherited. [2] The most common type is known as sickle cell anemia. [2] It results in an abnormality in the oxygen-carrying protein haemoglobin found in red blood cells. [2] This leads to a rigid, sickle -like shape under ...
GENE-Counter is a Perl pipeline for RNA-Seq differential gene expression analyses. Gene-counter performs alignments with CASHX, Bowtie, BWA or other SAM output aligner. Differential gene expression is run with three optional packages (NBPSeq, edgeR and DESeq) using negative binomial distribution methods.
Mutations can involve the duplication of large sections of DNA, usually through genetic recombination. [ 10 ] These duplications are a major source of raw material for evolving new genes, with tens to hundreds of genes duplicated in animal genomes every million years. [ 11 ] Most genes belong to larger gene families of shared ancestry ...
Genetics is the study of genes, genetic variation, and heredity in organisms. [1][2][3] It is an important branch in biology because heredity is vital to organisms' evolution. Gregor Mendel, a Moravian Augustinian friar working in the 19th century in Brno, was the first to study genetics scientifically.
The World Health Organization declared the recent outbreak of the disease a public health emergency of international concern after the new variant was identified. The number of mpox cases in ...
The list of organisms by chromosome count describes ploidy or numbers of chromosomes in the cells of various plants, animals, protists, and other living organisms. This number, along with the visual appearance of the chromosome, is known as the karyotype, [1][2][3] and can be found by looking at the chromosomes through a microscope.
However, the level of Hb F can be elevated in persons with sickle-cell disease and beta-thalassemia. Gene expression of hemoglobin before and after birth. Also identifies the types of cells and organs in which the gene expression (data on Wood W.G., (1976). Br. Med. Bull. 32, 282.) Abnormal forms that occur in diseases:
Horizontal gene transfer (HGT) or lateral gene transfer (LGT) [1][2][3] is the movement of genetic material between organisms other than by the ("vertical") transmission of DNA from parent to offspring (reproduction). [4] HGT is an important factor in the evolution of many organisms. [5][6] HGT is influencing scientific understanding of higher ...
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