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Sickle cell disease — also called sickle cell anemia — is a group of inherited disorders that affect hemoglobin , the major protein that carries oxygen in red blood cells. Normally, red blood cells are disc-shaped and flexible so they can move easily through the blood vessels. In sickle cell disease, red blood cells are misshaped, typically ...
However, in sickle cell disease, the body has trouble keeping up with the rate that the cells are being destroyed. This can lead to a low number of red blood cells, called anemia. The resulting anemia can cause a person to be easily tired with less energy. Normal red cells and sickled red cells.
View fact sheet. Crizanlizumab-tmca is approved for adults and children ages 16 years and older who have sickle cell disease. The medicine is given through an intravenous (IV) line in the vein once a month. The medicine helps prevent blood cells from sticking to blood vessel walls and blocking blood flow.
The National Institutes of Health (NIH) has supported research on sickle cell disease — also called sickle cell anemia — since before the NHLBI’s founding in 1948. With each passing decade, the NHLBI has kept a focus on advancing the understanding of sickle cell disease and improving clinical care for people who have it.
Overview. Hydroxyurea is an oral medicine that can help reduce sickle cell disease complications. This fact sheet will provide the facts about hydroxyurea, potential benefits and risks, and questions to ask your healthcare provider. Print Length:
It filters your blood and destroys old blood cells. In people who have sickle cell disease, red blood cells may get trapped in the spleen. This makes the spleen quickly grow larger than normal. Serious anemia can occur when red blood cells get trapped in the spleen. A large spleen may also cause pain in the left side of the belly.
Most people with sickle cell disease have this often-serious pain. It may occur in children as young as 1 year old. Serious pain linked with sickle cell disease often requires treatment in a clinic or hospital. Fatigue (extreme tiredness), shortness of breath, dizziness, and irregular heartbeat. These are symptoms of serious anemia.
Prenatal screening. Healthcare providers can also diagnose sickle cell disease before a baby is born. This can be done in two ways. The first uses a sample of amniotic fluid (the liquid in the sac surrounding a growing embryo). The second uses a sample taken from the placenta (the organ that attaches the umbilical cord to the womb).
Stress is an important and common trigger for sickle cell disease complications. Get enough good quality sleep. Not getting enough good quality sleep over time can lead to serious physical and mental health problems. The recommended amount of sleep for adults is 7 to 9 hours a day. Get regular physical activity.
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