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4.4 million (2015) [7] Deaths. 114,800 (2015) [8] Sickle cell disease ( SCD ), also simply called sickle cell, is a group of hemoglobin-related blood disorders typically inherited. [2] The most common type is known as sickle cell anemia. [2]
The estimated prevalence is 16% in people from Cyprus, 1% [71] in Thailand, and 3–8% in populations from Bangladesh, China, India, Malaysia and Pakistan . Estimates suggest that approximately 1.5% of the global population (80 – 90 million people) are β-thalassemia carriers. [72]
Sickle cell anemia affects about 72,000 people in the United States. Most Americans who have sickle cell anemia are of African descent. The disease also affects Americans from the Caribbean, Central America, and parts of South America, Turkey, Greece, Italy, the Middle East and East India.
More than 1 million people with sickle cell disease live in India, studies show, and more than 5 million are in sub-Saharan Africa.
The agency approved the treatment for patients with sickle cell disease and thalassemia who are 12 years old and over. Casgevy is made by Vertex Pharmaceuticals (Europe) Ltd. and CRISPR ...
The disease, which can stunt physical growth, is more common in malaria-prone regions, notably Africa and India, because carrying the sickle cell trait helps protect against severe malaria.
Sickle cell – The gene for HbS associated with sickle-cell is today distributed widely throughout sub-Saharan Africa, the Middle East, and parts of the Indian subcontinent, where carrier frequencies range from 5–40% or more of the population.
The Sickle Cell Disease Association of America, Inc. ( SCDAA) is a nonprofit organization with the sole purpose of supporting research, education and funding of individuals, families those who are impacted by sickle cell disease .
New gene therapies promise a cure for sickle cell disease, and Dongre says he’s “praying the treatment should come to us.” Vast inequities cut much of the world off from gene therapy in general.
Felix Israel Domeno Konotey-Ahulu FGA, FRCPSG, FRCP, FWACP (born 12 July 1930) is a Ghanaian physician and scientist who is Kwegyir Aggrey Distinguished Professor of Human Genetics at the University of Cape Coast, Ghana, and a consultant physician/ genetic counsellor, Haemoglobinopathy/Sickle Cell States, in Harley Street, London. [4] He is one of the world's foremost experts on sickle-cell ...